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Meningococcal Prophylaxis: Problems with Minocycline

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Pharmacology of Antibiotics

Part of the book series: Chemotherapy ((CT,volume 4))

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Summary

Minocycline (7-dimethyl amino-6-demethyl tetracycline) is a tetracycline derivative that has been advocated as the drug of choice in the treatment of meningococcal carriers. The frequency and severity of side effects reported with minocycline in initial studies were infrequent and mild. We studied a group of thirty patients given minocycline as prophylaxis for a case of meningococcal meningitis who experienced a large number of side effects often limiting normal daily activity.

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References

  1. Center for Disease Control (1975), Morbidity and Mortality Weekly Report, 24, 9.

    Google Scholar 

  2. Center for Disease Control (1975), Morbidity and Mortality Weekly Report, 24, 55.

    Google Scholar 

  3. Devine, L.F., Johnson, D.P., Hagerman, C.R., Pierce, W.E., Rhode, S.L. III and Peckinpaugh, R.O. (1971), American Journal of Epidemiology, 93, 337.

    PubMed  CAS  Google Scholar 

  4. Frisk, A.R., and Tunevall, G. (1969), Antimicrobial Agents and Chemotherapy — 1968, 335.

    Google Scholar 

  5. Guttler, R.B., Counts, G.W., Avent, C.K., and Beaty, H.N. (1971), The Journal of Infectious Disease, 124, 199.

    Article  CAS  Google Scholar 

  6. Guttler, R.B., and Beaty, H.N. (1972), Antimicrobial Agents and Chemotherapy, 1, 397.

    PubMed  CAS  Google Scholar 

  7. Leedom, J.M., Ivler, D., Mathies, A.W. , Thrupp, L.D., Portnoy, B., and Wehrle, P.F. (1965), New England Journal of Medicine, 273, 1395.

    Article  PubMed  CAS  Google Scholar 

  8. Munford, R.S., de Vasconcelos, Z.J.S., Phillips, C.J., Gelli, D.S., Gorman, G.W., Risi, J.H., and Feldman, R.A. (1974). The Journal of Infectious Diseases, 129, 644.

    Article  PubMed  CAS  Google Scholar 

  9. Williams, D.N., Laughlin, L.W., and Lee, Y-H (1974), The Lancet, 2, 744.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine, Infectious Disease Unit, University of Vermont College of Medicine, Burlington, Vermont, USA

    Dieter W. Gump & W. Lee Fanning

Authors
  1. Dieter W. Gump
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  2. W. Lee Fanning
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Editor information

Editors and Affiliations

  1. The London Hospital Medical College, London, UK

    J. D. Williams

  2. East Birmingham Hospital, Birmingham, UK

    A. M. Geddes

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© 1976 Plenum Press, New York

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Gump, D.W., Fanning, W.L. (1976). Meningococcal Prophylaxis: Problems with Minocycline. In: Williams, J.D., Geddes, A.M. (eds) Pharmacology of Antibiotics. Chemotherapy, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3123-0_52

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  • DOI: https://doi.org/10.1007/978-1-4684-3123-0_52

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3125-4

  • Online ISBN: 978-1-4684-3123-0

  • eBook Packages: Springer Book Archive

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