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Immunoadjuvant Properties of Liposomes

  • Chapter
Targeting of Drugs

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 47))

Abstract

Liposomes are artificially prepared spheres of concentric phospholipid bilayers separated by aqueous compartments. They form when water insoluble phospholipids are confronted with water. The phospholipid molecules try to reach a conformation in which their hydrophobic fatty acid groups are not in direct contact with water. The formation of phospholipid bilayers in which the relatively hydrophylic head groups are localized on both outer parts of the bilayers, whereas the hydrophobic fatty acid groups are localized directly opposite to each other in the inner part of the bilayer is a logical consequence.

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Authors and Affiliations

  1. Medical Faculty, Free University, Postbox 7161, 1007 MC, Amsterdam, The Netherlands

    N. van Rooijen & Ria van Nieuwmegen

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  1. N. van Rooijen
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  2. Ria van Nieuwmegen
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Editors and Affiliations

  1. Clinical Research Centre, Harrow, UK

    Gregory Gregoriadis  & Judith Senior  & 

  2. International Institute of Cellular and Molecular Pathology, Brussels, Belgium

    André Trouet

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van Rooijen, N., van Nieuwmegen, R. (1982). Immunoadjuvant Properties of Liposomes. In: Gregoriadis, G., Senior, J., Trouet, A. (eds) Targeting of Drugs. NATO Advanced Study Institutes Series, vol 47. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4241-0_18

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  • DOI: https://doi.org/10.1007/978-1-4684-4241-0_18

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