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Genetic Variants of Cultured Animal Cells

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Somatic Cell Genetics

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 50))

Abstract

It has been clear for a number of years that the functional analysis of biological systems is highly dependent upon the availability of a large number of mutants of broad phenotypic classes. It was with this understanding that our laboratory undertook about ten years ago to develop methods for selection of mutants in somatic cells. Over this decade the field has developed extremely rapidly both in terms of methodological expertise and in the wide spectrum of mutants which can now be used for studies on gene function and regulation.

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Authors and Affiliations

  1. Department of Genetics, Hospital for Sick Children, Toronto, Ontario, Canada

    Peter N. Ray & Louis Siminovitch

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  1. Peter N. Ray
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  2. Louis Siminovitch
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  1. Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, USA

    C. Thomas Caskey  & D. Christopher Robbins  & 

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© 1982 Plenum Press, New York

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Ray, P.N., Siminovitch, L. (1982). Genetic Variants of Cultured Animal Cells. In: Caskey, C.T., Robbins, D.C. (eds) Somatic Cell Genetics. NATO Advanced Study Institutes Series, vol 50. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4256-4_9

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  • DOI: https://doi.org/10.1007/978-1-4684-4256-4_9

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