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Peritoneal Macrophages Release Prostaglandin E and Thromboxane B2 in Response to C3b

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Macrophages and Natural Killer Cells

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 155))

Abstract

Macrophages have surface receptors for C3b, the larger product cleaved from complement component C3 upon activation of both the classical and alternative complement pathways (1). We have investigated whether or not C3b stimulates macrophages to release prostaglandin E (PGE) and thromboxane B2 (TXB2), metabolites of arachidonic acid produced in the cyclooxygenase pathway (2).

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Author information

Authors and Affiliations

  1. Inst. for Medical Microbiology, Univ. Mainz, Hochhaus Augustuspl., D-6500, Mainz, Germany

    Ulrich Hadding, Hans-Peter Hartung, Heinrich Rasokat & Diethard Gemsa

  2. Inst. of Immunology, Univ. Heidelberg, Germany

    Ulrich Hadding, Hans-Peter Hartung, Heinrich Rasokat & Diethard Gemsa

Authors
  1. Ulrich Hadding
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  2. Hans-Peter Hartung
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  3. Heinrich Rasokat
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  4. Diethard Gemsa
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Editor information

Editors and Affiliations

  1. College of Medicine, University of Florida, Gainesville, Florida, USA

    Sigurd J. Normann

  2. Department of Medicine, Swiss Research Institute, Davos, Switzerland

    Ernst Sorkin

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© 1982 Plenum Press, New York

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Hadding, U., Hartung, HP., Rasokat, H., Gemsa, D. (1982). Peritoneal Macrophages Release Prostaglandin E and Thromboxane B2 in Response to C3b. In: Normann, S.J., Sorkin, E. (eds) Macrophages and Natural Killer Cells. Advances in Experimental Medicine and Biology, vol 155. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4394-3_56

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  • DOI: https://doi.org/10.1007/978-1-4684-4394-3_56

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4396-7

  • Online ISBN: 978-1-4684-4394-3

  • eBook Packages: Springer Book Archive

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