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Recent Advances in Thymic Hormone Research

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New Experimental Modalities in the Control of Neoplasia

Part of the book series: NATO ASI Series ((NSSA,volume 120))

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Abstract

The essential role of the thymus gland in the development of a competent immune system was established by experiments in which it was found that the surgical removal of the thymus within 24 hours after birth, resulted in a dramatic impairment of the immune function (1,2). Neonatal thymectomy was also accompanied by a high incidence of early death due primarily to overwhelming infections. Additionally, recent evidence suggests that the thymus gland might be critical not only in mediating lymphocyte maturation and differentiation, but also in maintaining a normal immune balance by modulating normal immune response (3–12).

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  1. Departments of Medicine and Biochemistry, The George Washington University School of Medicine, Washington DC, USA

    Marcelo B. Sztein & Allan L. Goldstein

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  1. Marcelo B. Sztein
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  1. University of Frankfurt, Frankfurt am Main, Federal Republic of Germany

    Prakash Chandra

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© 1986 Plenum Press, New York

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Sztein, M.B., Goldstein, A.L. (1986). Recent Advances in Thymic Hormone Research. In: Chandra, P. (eds) New Experimental Modalities in the Control of Neoplasia. NATO ASI Series, vol 120. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5242-6_10

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