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Immunohistochemical and Morphological Observations of Macrophages in the Human Ovary

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Growth Factors and the Ovary

Abstract

Macrophages have been identified within the corpus luteum of several species, including human (1–3). In addition to their well recognized phagocytic property, macrophages have been shown to exert other influences in luteal tissue. Recently, Kirsch et al. reported that macrophages secrete substances that stimulate luteal cell progesterone production in the mouse corpus luteum (4), and Halme et al. suggested that peritoneal macrophages may exert luteotropic effects on human granulosa-luteal cells (5).

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References

  1. Bulmer D.The Mstochemistry of ovarian macrophages in the rat. J Anat 1964;98:313–9.

    PubMed  CAS  Google Scholar 

  2. Gillim SW, Christensen KA, McLennan CE. Fine structure of the human menstrual corpus luteum at its stage of maximum secretory activity. Am J Anat 1969; 126:409–28.

    Article  PubMed  CAS  Google Scholar 

  3. Paavola LG. The corpus luteum of the guinea pig. Fine structure at the time of maximum secretion and during regression. Am J Anat 1977; 150:565–604.

    Article  PubMed  CAS  Google Scholar 

  4. Kirsch TM, Friedman AC, Vogel RL, Flickinger GL. Macrophages in corpora lutea of mice: characterization and effects on steroid secretion. Biol Reprod 1981; 25:629–38.

    Article  PubMed  CAS  Google Scholar 

  5. Halme J, Hammond MG, Syrop CH, Tolbert LM. Peritoneal macrophages modulate human granulosa-luteal cell progesterone production. J Clin Endocrinol Metab 1985; 61:912–6.

    Article  PubMed  CAS  Google Scholar 

  6. Takeya M, Hsiao L, Takahashi K. A new monoclonal antibody TRPM-3, binds specifically to certain rat macrophage populations: immunohistochemical and im-munoelectron microscopic analysis. J Leukocyte Biol 1987; 41:187–95.

    PubMed  CAS  Google Scholar 

  7. Tapanainen J, Leinonen PJ, Tapanainen P, Yamamoto M, Jaffe RB. Regulation of human granulosa-luteal cell progesterone production and proliferation by gonadotropins and growth factors. Fertil Steril 1987; 48:576–80.

    PubMed  CAS  Google Scholar 

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© 1989 Plenum Press, New York

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Katabuchi, H., Fukumatsu, Y., Okamura, H. (1989). Immunohistochemical and Morphological Observations of Macrophages in the Human Ovary. In: Hirshfield, A.N. (eds) Growth Factors and the Ovary. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5688-2_54

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  • DOI: https://doi.org/10.1007/978-1-4684-5688-2_54

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5690-5

  • Online ISBN: 978-1-4684-5688-2

  • eBook Packages: Springer Book Archive

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