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Proteoglycans, Lipoproteins, and Atherosclerosis

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Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 285))

Abstract

Extracellular matrix proteoglycans play an important role in main taining structural integrity and normal function of the arterial wall. These macromolecules provide structural links between fibrous and cellular elements, contribute to viscoelastic properties, regulate permeability and retention of plasma components through the matrix, control vascular cell growth, affect hemostasis and interact with lipoproteins (1,2). These functional properties indicate that proteoglycans are clearly involved in the pathogenesis of atherosclerosis.

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References

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Author information

Authors and Affiliations

  1. Department of Medicine, Louisiana State University School of Medicine, 1542 Tulane Avenue, New Orleans, LA, 70112, USA

    S. R. Srinivasan, B. Radhakrishnamurthy, P. Vijayagopal & G. S. Berenson

  2. Department of Biochemistry, Louisiana State University School of Medicine, 1542 Tulane Avenue, New Orleans, LA, 70112, USA

    S. R. Srinivasan & B. Radhakrishnamurthy

Authors
  1. S. R. Srinivasan
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  2. B. Radhakrishnamurthy
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  3. P. Vijayagopal
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  4. G. S. Berenson
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Editor information

Editors and Affiliations

  1. Research Foundation on Atherosclerosis, B-1000, Brussels, Belgium

    Claude L. Malmendier

  2. Lipoprotein and Atherosclerosis Resaerch Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, 73104, USA

    P. Alaupovic

  3. Molecular Disease Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA

    H. Bryan Brewer Jr.

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© 1990 Plenum Press, New York

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Srinivasan, S.R., Radhakrishnamurthy, B., Vijayagopal, P., Berenson, G.S. (1990). Proteoglycans, Lipoproteins, and Atherosclerosis. In: Malmendier, C.L., Alaupovic, P., Brewer, H.B. (eds) Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics. Advances in Experimental Medicine and Biology, vol 285. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5904-3_45

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  • DOI: https://doi.org/10.1007/978-1-4684-5904-3_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5906-7

  • Online ISBN: 978-1-4684-5904-3

  • eBook Packages: Springer Book Archive

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