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Catabolism in Acute Renal Failure: Importance of Glucocorticoids and Lysosomal Enzymes

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Acute Renal Failure

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 212))

Abstract

Renal failure has been previously shown to be a catabolic event1–6. There is growing evidence for a certain role of proteolytic enzymes in the catabolism of acute uremia7–13 Thus, frank proteolytic activity has been demonstrated in ultrafiltrated plasma fractions, in the urine and bronchoalveolar-lavage (BAL) fluid14–15 The type of proteinases involved, is up to now not totally defined. There are some data, which indicate a participation of broad spectrum serine proteinases in the BAL-fluid and in the plasma of ureter-ligated rats16.

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Author information

Authors and Affiliations

  1. Department of Medicine, University of Wurzburg, Germany

    August Heidland, Roland M. Schaefer, Joachim Weipert, Ekkehart Heidbreder & Markus Teschner

  2. Department of Dermatology, University of Wurzburg, Germany

    Gernot Peter

  3. Department of Medicine, University of Freiburg, Freiburg, Germany

    Walter H. Horl

Authors
  1. August Heidland
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  2. Roland M. Schaefer
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  4. Ekkehart Heidbreder
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  7. Walter H. Horl
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Editors and Affiliations

  1. University of Bari, Bari, Italy

    Alberto Amerio  & Pasquale Coratelli  & 

  2. University of Southern California, Los Angeles, California, USA

    Vito M. Campese  & Shaul G. Massry  & 

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© 1987 Plenum Press, New York

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Heidland, A. et al. (1987). Catabolism in Acute Renal Failure: Importance of Glucocorticoids and Lysosomal Enzymes. In: Amerio, A., Coratelli, P., Campese, V.M., Massry, S.G. (eds) Acute Renal Failure. Advances in Experimental Medicine and Biology, vol 212. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8240-9_5

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  • DOI: https://doi.org/10.1007/978-1-4684-8240-9_5

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