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Computerized 3-D Reconstruction of Small Blood Vessels from High Voltage Electron-Micrographs of Thick Serial Cross Sections

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Vascular Endothelium in Health and Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 242))

Abstract

Every cell and organ system in the body depends on the circulation of blood for appropriate nutrients, humoral message exchange, and removal of waste. The heart and the large blood vessels are indispensable as pump and plumbing. Blood flow according to tissue needs, however, and body weight economy in terms of total blood volume, requires complex control mechanisms and an intricate distribution system peripherally, particularly in the microcirculation which consists of vessels less than 100 µ. The smallest arteries and arterioles are generally considered the key vessels mediating the distribution of flow by changing their diameters and thus flow resistance. The structural aspects of these vessels thus become crucial for the understanding of the mechanisms that allow the system to operate in optimal harmony — the harmony that we call good health.

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© 1988 Plenum Press, New York

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Horn, L., Krajewski, W.S., Paul, P.K., Song, M.J., Sydor, M.J. (1988). Computerized 3-D Reconstruction of Small Blood Vessels from High Voltage Electron-Micrographs of Thick Serial Cross Sections. In: Chien, S. (eds) Vascular Endothelium in Health and Disease. Advances in Experimental Medicine and Biology, vol 242. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8935-4_5

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  • DOI: https://doi.org/10.1007/978-1-4684-8935-4_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8937-8

  • Online ISBN: 978-1-4684-8935-4

  • eBook Packages: Springer Book Archive

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