Abstract
Adherent or accessory cells, previously indicated as “A”-cells are of paramount importance in the immune response in vitro as well as in vivo. The nonlymphoid adherent population of peritoneal exudate cells, which have phagocytic properties, comprise the accessory cells which have to be present in lymphoproliferative responses in vitro. Most of these cells were obviously macrophages. However, they constitute a heterogeneous population of cells. It appeared that only a minority (8–15%) of these cells bear the Ia determinants of the immune response gene complex (1) which determines their antigen presenting function. Moreover, macrophages may change their properties in this respect during adhesion in vitro (2).
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References
R.H. Schwartz, H.B. Dickler, H.D. Sachs, and B.D. Schwartz. Scand. J. Immunol. 5:731 (1976).
C. Cowing, B.D. Schwartz, and H.B. Dickler. J. Immunol. 120:378 (1978).
E.C.M. Hoefsmit, _in: “Mononuclear phagocytes in immunity, infection and pathology,” p. 129, R. van Fürth, ed., Blackwell, Oxford (1975).
E.C.M. Hoefsmit, E.W.A. Kamperdijk, and B.M. Balfour, in: “Mononuclear phagocytes, functional aspects,” vol. 2, p. 1809, R. van Fürth, ed., Martinus Nijhoff, The Hague (1980).
I. Silberberg, R.L. Baer, S.A. Rosenthal, G.J. Thorbecke and V. Berezowsky. Clin. Res. 23:231A (1975).
R.M. Steinman, and Z.A. Cohn. J. Exp. Med. 137:1142 (1973).
R.M. Steinman, and M.C. Nussenzweig. Immunol. Rev. 53:127 (1980).
G.J.V. Nossal, A. Abbot, J. Mitchell, and Z. Lummus. J. Exp. Med. 127:277 (1968).
E.C.M. Hoefsmit, E.W.A. Kamperdijk, H.R. Hendriks, R.H.J. Beelen, and B.M. Balfour, in: “The reticuloendothelial system: a comprehensive treatise,” vol. I Morphology, p. 417, I. Carr, and W.T. Daems, eds., Plenum Publishing Corporation, New York (1980).
H.L. Langevoort, Z.A. Cohn, J.G. Hirsch, J.H. Humphrey, W.G. Spector, and R. van Fürth, in: “Mononuclear phagocytes,” p. 1, R. van Furth, ed., Blackwell, Oxford (1970).
Z.A. Cohn, and E. Wiener. J. Exp. Med. 118:991 (1963).
S.G. Rice, and M. Fischman. Cell. Immunol. 11:130 (1974).
W.S. Walker. Nature New Biology 229:211 (1971).
W.S. Walker. Immunology 26:1025 (1974).
K.-C. Lee, A. Wilkinson, and M. Wong. Cell. Immunol. 48:79 (1979).
E. Tzehoval, R. de Baetselier, M. Feldman, and S. Segal. Eur. J. Immunol. 11:323 (1981).
R.V. Blanden, M.J. Lefford, and G.B. Mackaness. J. Exp. Med. 129:1079 (1969).
D.J. Beller, J.M. Kiely, and E.R. Unaue. J. Immunol. 124: 1426 (1980).
J.B. Toews, P.R. Bergstresser, and J. Wayne Streilein. J. Invest. Dermatol. 75:78 (1980).
I. Silberberg-Sinakin, and G.J. Thorbecke. J. Invest. Dermatol. 75:61 (1980).
H. Ebner, and G. Niebauer. Arch. Klin. U. Exp. Derm. 229:217 (1967).
G. Stingl, K. Tamaki, and S.I. Katz. Immunol. Rev. 53:149 (1980).
R.H. Kelly, B.M. Balfour, J.A. Armstrong, and S. Griffiths. Anat. Rec. 190:5 (1978).
E.W.A. Kamperdijk, E.M. Raaymakers, J.H.S. de Leeuw, and E.C.M. Hoefsmit. Cell Tiss. Res. 192:1 (1978).
W.H. Gerneke. J. South Afr. Veterin. Assoc. 51/3:137 (1980).
A.M. Dijvestijn, and E.C.M. Hoefsmit. Cell Tiss. Res., in press.
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© 1982 Plenum Press, New York
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Hoefsmit, E.C.M. (1982). Macrophages, Langerhans Cells, Interdigitating and Dendritic Accessory Cells: A Summary. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_65
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DOI: https://doi.org/10.1007/978-1-4684-9066-4_65
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