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Endocrine Tumors of the Pancreas

  • Chapter
The Diabetic Pancreas

Abstract

The endocrine tumors of the pancreas are usually called islet cell tumors (adenomas or carcinomas of the islets of Langerhans). This name implies their origin from the pancreatic islets. However, this assumption is not justified. The histologic structure of endocrine pancreatic tumors is not markedly different from other endocrine tumors, and not all hormones produced by these tumors are normal products of the islets of Langerhans. The still controversial question of the origin of pancreatic tumors will be discussed later. Any nomenclature anticipating this undecided problem should be avoided. This applies also to the term “nesidioblastoma,” introduced in 1938 by Laidlaw.1 Laidlaw named the cells that differentiate from the duct epithelium to form islets “nesidioblasts,” their proliferation “nesidioblastosis,” and their tumors “nesidioblastomas.”

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  1. Medizinische Klinik und Poliklinik, Universität Göttingen, D-3400, Göttingen, West Germany

    Werner Creutzfeldt

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  1. University of California Irvine Medical Center, Orange, California, USA

    Bruno W. Volk M.D.  & Edward R. Arquilla M.D., Ph.D.  & 

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Creutzfeldt, W. (1985). Endocrine Tumors of the Pancreas. In: Volk, B.W., Arquilla, E.R. (eds) The Diabetic Pancreas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0348-1_24

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