Abstract
Contrast agent-assisted imaging of vasculature is widely employed during the diagnosis of many vascular and neoplastic diseases [1]. Conventional X-ray contrast media are ionic or neutral low molecular weight iodine-containing organic molecules and are able to delineate the vascular bed for a limited time following rapid extravasation into the interstitial space. Such a rapid disappearance of contrast material from the blood narrows the examination time window down to several minutes for the majority of diagnostic applications. Peak enhancement of the aorta takes place 10 to 20 s after the beginning of the injection. Within 2 min, the signal from the blood pool drops approximately fivefold [2].
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Kim, E.E. (2001). Computed Tomography and Ultrasound Contrast Agents. In: Kim, E.E., Yang, D.J. (eds) Targeted Molecular Imaging in Oncology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3505-5_15
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DOI: https://doi.org/10.1007/978-1-4757-3505-5_15
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