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Synthesis of Radiopharmaceuticals Via Organoboranes

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New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

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Abstract

Radiopharmaceuticals containing complex functional groups are playing an increasing role in diagnostic nuclear medicine due to new developments in the instrumentation used for single-photon emission computerized tomography (SPECT)1 and positron emission tomography (PET).2 These computerized systems permit noninvasive, in vivo, three-dimensional imaging of organs after administration of appropriate agents labeled with short-lived nuclides.3 The techniques are used for in vivo pharmacokinetics, organ imaging, evaluation of organ function, and physiological mapping. They complement the traditional X-ray scan and are’partially responsible for the tremendous upsurge in the use of radiopharmaceuticals in hospitals today.

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Author information

Authors and Affiliations

  1. Department of Chemistry, The University of Tennessee, Knoxville, Tennessee, USA

    George W. Kabalka

  2. Department of Radiology, The University of Tennessee, Knoxville, Tennessee, USA

    George W. Kabalka & Mark M. Goodman

Authors
  1. George W. Kabalka
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  2. Mark M. Goodman
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Editor information

Editors and Affiliations

  1. The University of Texas Health Science Center, Houston, Texas, USA

    Ali M. Emran

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© 1991 Springer Science+Business Media New York

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Kabalka, G.W., Goodman, M.M. (1991). Synthesis of Radiopharmaceuticals Via Organoboranes. In: Emran, A.M. (eds) New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0626-7_27

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  • DOI: https://doi.org/10.1007/978-1-4899-0626-7_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0628-1

  • Online ISBN: 978-1-4899-0626-7

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