Abstract
By definition, sentinel lymph node(s) (SLN) is the first lymph node to receive lymphatic drainage from a particular anatomic area and thus it will most likely contain metastatic deposits from any tumor located in that area. Within the last 20 years, evaluation of SLN has become the most popular method of early staging of several malignancies, including breast carcinoma and melanoma. SLN biopsy has lower number/degree of side effects that regional lymphadenectomy; also the selection of a small number of lymph nodes allows intense analysis by Pathology (hematoxylin and eosin sections and immunohistochemistry). This chapter describes the pathology analysis of SLN with especial emphasis on the use of immunohistochemistry.
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Prieto, V.G., Shea, C.R., Reed, J.A. (2015). Capsular (Nodal) Nevus Versus Metastatic Melanoma. In: Shea, C., Reed, J., Prieto, V. (eds) Pathology of Challenging Melanocytic Neoplasms. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1444-9_17
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DOI: https://doi.org/10.1007/978-1-4939-1444-9_17
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