Abstract
The technology described in the previous two chapters, recombinant DNA technology, gene knockouts, polymerase chain reactions (PCR), and transgenics, has provided anew set of tools and opportunities for examining normal and aberrant gene function. As a result, oncogenes, high-density lipoprotein (HDL) receptor, and the cystic fibrosis transmembrane (conductance) regulator (CFTR) have been identified, thereby providing new insight into the biochemical basis of cancer, atherosclerosis, and cystic fibrosis (CF), respectively. The biochemical protein molecules that emerge in the biochemical pathways that define these illnesses become potential drug targets for manipulation of disease progression.
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Wu-Pong, S. (1999). Treatment Options. In: Wu-Pong, S., Rojanasakul, Y. (eds) Biopharmaceutical Drug Design and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-705-5_4
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DOI: https://doi.org/10.1007/978-1-59259-705-5_4
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-4757-4644-0
Online ISBN: 978-1-59259-705-5
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