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Cannabis and Natural Cannabis Medicines

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Marijuana and the Cannabinoids

Part of the book series: Forensic Science And Medicine ((FSM))

Abstract

Cannabis plants produce many compounds of possible medical importance. This chapter briefly explains the life cycle, origin, early evolution, and domestication of Cannabis, plus provides a brief history of drug Cannabis breeding and looks into the future of Cannabis as a source of medicines. Cannabis is among the very oldest of economic plants providing humans with fiber for spinning, weaving cloth, and making paper; seed for human foods and animal feeds; and aromatic resin containing compounds of recreational and medicinal value. Human selection for varying uses and natural selection pressures imposed by diverse introduced climates have resulted in a wide variety of growth forms and chemical compositions. Innovative classical breeding techniques have been used to improve recreational drug forms of Cannabis, resulting in many cannabinoid-rich cultivars suitable for medical use. The biosynthesis of cannabinoid compounds is unique to Cannabis, and cultivars with specific chemical profiles are being developed for diverse industrial and pharmaceutical uses.

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References

  1. Clarke, R. C. (1981) Marijuana Botany, Berkeley: Ronin Publishing.

    Google Scholar 

  2. Mandolino, G. and Ranalli, P. (1999) Advances in biotechnological approaches for hemp breeding and industry, in Advances in Hemp Research. (Ranalli, P.,ed.), Haworth Press, New York, pp. 185–211.

    Google Scholar 

  3. Hong, S., Song, S-J., and Clarke, R. C. (2003) Female-associated DNA polymorphisms of hemp (Cannabis sativa L.) J. Indust. Hemp 1, 5–9.

    Google Scholar 

  4. Small, E. and Antle, T. (2003) A preliminary study of pollen dispersal in Cannabis sativa in relation to wind direction. J. Indust. Hemp 8, 37–50.

    Article  Google Scholar 

  5. Deferne, J-L. and Pate, D. W. (1996) Hemp seed oil: a source of valuable essential fatty acids. J. Int.Hemp Assoc. 3, 1, 4–7.

    Google Scholar 

  6. Grigoriev, O. V. (2002) Application of hempseed (Cannabis sativa L.) oil in treatment of ear, nose and throat (ENT) disorders. J. Indust. Hemp 7, 5–15.

    Article  CAS  Google Scholar 

  7. Meier, C. and Mediavilla, V. (1998) Factors influencing the yield and the quality of hemp (Cannabis sativa L.) essential oil. J. Int. Hemp Assoc. 5, 16–20.

    Google Scholar 

  8. Liu, Y. and Tang, X. (1984) Green seedling of hemp acquired by tissue culture. China’s Fibre Crops 2, 19, 29 [in Chinese].

    Google Scholar 

  9. Hendriks, H., Malingre, T. M., Batterman, S., and Bos, R. (1978) The essential oil of Cannabis sativa L. Pharm. Weekbl. 113, 413–424.

    CAS  Google Scholar 

  10. Ross, R. A. and ElSohly, M. A. (1996) The volatile oil composition of fresh and air-dried buds of Cannabis sativa L. J. Nat. Prod. 59, 49–51.

    Article  PubMed  CAS  Google Scholar 

  11. Clarke, R. C. (1998) Hashish!, Red Eye Press, Los Angeles.

    Google Scholar 

  12. Pate, D. W. (1994) Chemical ecology of Cannabis. J. Int. Hemp Assoc. 1, 29, 32–37.

    Google Scholar 

  13. McPartland, J., Clarke, R. C., and Watson, D. P. (2000) Hemp Diseases and Pests, CAB International, Wallingford, UK.

    Google Scholar 

  14. Briosi, G. and Tognini, F. (1894) Intorno alla anatomia della canapa (Cannabis sativa L.) parte prima-organi sessual, Atti dell’ Instituto Botanico di Pavia, Serie I, Vol. 3.

    Google Scholar 

  15. McPartland, J. and Mediavilla, V. (2002) Cannabis and Cannabinoids: Pharmacology and Therapeutic Potential (Grotenhermen, F. and Russo, E., eds.), Haworth Integrative Healing Press, New York, pp. 401–409.

    Google Scholar 

  16. Taura, F., Morimoto, S., Shoyama, Y., and Mechoulam, R. (1995) First direct evidence for the mechanism of delta-1-tetrahydrocannabinol acid biosynthesis. J. Am. Chem. Soc. 117, 9766–9767.

    Article  CAS  Google Scholar 

  17. Taura, F., Morimoto, S., and Shoyama, Y. (1996) Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid. J. Biol. Chem. 271, 17411–17416.

    Article  PubMed  CAS  Google Scholar 

  18. Flachowsky, H., Schumann, E., Weber, W. E., and Peil, A. (2000) AFLP-marker for male plants of hemp (Cannabis sativa L.) Poster presented at the 3rd Bioresource Hemp Symposium, Wolfsburg, Germany, September 13-16.

    Google Scholar 

  19. de Meijer, E. P. M., Bagatta, M., Carboni, A., et al. (2003) The inheritance of chemical phenotype in Cannabis sativa L. Genetics 163, 335–346.

    PubMed  Google Scholar 

  20. Small, E. and Cronquist, A. (1976) A practical and natural taxonomy for Cannabis. Taxon 25, 405–435.

    Article  Google Scholar 

  21. Schultes, R. E., Klein, W. M., Plowman, T., and Lockwood, T. E. (1974) Cannabis: an example of taxonomic neglect. Botanical Museum Leaflets, Harvard University 23, 337–364.

    Google Scholar 

  22. Serebriakova, T. I. (1940) Fiber plants, in Flora of Cultivated Plants. Vol.4, Part1 (Wulff, E. V., ed.), State Printing Office, Moscow and Leningrad [in Russian].

    Google Scholar 

  23. Vavilov, N. and Bukinich, D. D. (1929) Agricultural Afghanistan. Bull. Appl. Bot. Genet. Plant Breed.Supp. 33, 378–382, 474, 480, 584-585, 604.

    Google Scholar 

  24. Hillig, K. W. and Mahlberg, P. G. (2004) Genetic evidence for speciation in Cannabis (Cannabaceae). Genet. Resources Crop Evol. 52, 161–180.

    Article  Google Scholar 

  25. de Meijer, E. P. M. (1999) Cannabis germplasm resources, in Advances in Hemp Research (Ranalli, P., ed.), Haworth Press, New York, pp. 133–151.

    Google Scholar 

  26. HortaPharm, personal communication (1998) HortaPharm BV develops industrial Cannabis cultivars and provided the starting materials GW Pharmaceuticals breeding project in the United Kingdom.

    Google Scholar 

  27. Gierenger, D. (1999) Medical Cannabis potency testing. Bull. Multidisc. Assoc. Psychedel. Stud. 9, 20–22.

    Google Scholar 

  28. MacKinnon, L. (2003) Genetic transformation of Cannabis sativa Linn: a multi purpose fibre crop, doctoral thesis, University of Dundee, Scotland.

    Google Scholar 

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© 2007 Humana Press Inc., Totowa, New Jersey

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Clarke, R.C., Watson, D.P. (2007). Cannabis and Natural Cannabis Medicines . In: ElSohly, M.A. (eds) Marijuana and the Cannabinoids. Forensic Science And Medicine. Humana Press. https://doi.org/10.1007/978-1-59259-947-9_1

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  • DOI: https://doi.org/10.1007/978-1-59259-947-9_1

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-456-2

  • Online ISBN: 978-1-59259-947-9

  • eBook Packages: MedicineMedicine (R0)

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