Abstract
Genetics is an emerging field in cardiovascular medicine. Remarkably, less than 50 yr ago genetics was a nascent field of basic research with little apparent relevance to cardiovascular science or any other medical subspecialty. Yet today cardiovascular genetics is a discipline that fully integrates high technology laboratory investigation and clinical medicine. From this unusual hybrid have emerged discoveries that precisely identify cause in here-to-for “idiopathic” disorders, that provide fundamental insights into disease processes, and that delineate subtypes in well-defined pathologies. Insights from these discoveries uproot traditional anatomic classifications of disease and integrate cell physiology and molecular biochemistry into the study of pathology. For researchers, practitioners, and patients alike, cardiovascular genetics has a growing impact on the definition and diagnosis of disease, on explaining prognosis, and expanding treatments.
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Ho, C.Y., Seidman, C.E. (2006). Inherited Cardiomyopathies. In: Runge, M.S., Patterson, C. (eds) Principles of Molecular Medicine. Humana Press. https://doi.org/10.1007/978-1-59259-963-9_11
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DOI: https://doi.org/10.1007/978-1-59259-963-9_11
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