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Cardiovascular Disease in Women with Diabetes

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Diabetes in Women

Part of the book series: Contemporary Diabetes ((CDI))

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Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women in the USA. Women with diabetes are at a greater risk of CVD than men with diabetes. In this chapter we review the various mechanisms by which hyperglycemia potentiates this increased CVD risk, including coagulation abnormalities as well as endothelial dysfunction. Where applicable, sex-specific differences in these mechanisms are highlighted. Finally, the impact and burden of diabetes on CVD as well as screening for CVD in women are discussed.

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Acknowledgments

The authors would like to thank Rieanne Brinkmann and Brenda Hunter for their assistance in the manuscript preparation. Dr. Sowers is a member of the Speakers’ Bureau and has received grant funding from Novartis Pharmaceutical Company. Dr. Sowers is a member of the Speakers’ Bureau for Merck Pharmaceutical Company. Dr. Sowers is on the Advisory Board and has received grant funding from Forest Research Institute.

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Authors and Affiliations

  1. Division of Endocrinology, Diabetes and Metabolism, University of Missouri – Columbia, Columbia, MO, USA

    James R. Sowers

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  1. Sonia Gajula
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  2. Ashwini Reddy
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  3. L. Romayne Kurukulasuriya
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  4. Camila Manrique
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  5. Guido Lastra
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  6. James R. Sowers
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Editors and Affiliations

  1. Dept. Medicine, University Ioannina, Ioannina, 455 10, Greece

    Agathocles Tsatsoulis

  2. Dept. Internal Medicine, University of Michigan, E. Medical Center Dr. 1500, Ann Arbor, 48109-0354, U.S.A.

    Jennifer Wyckoff

  3. Dept. Medicine, Harvard Medical School, Joslin Place 1, Boston, 02215, U.S.A.

    Florence M. Brown

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Gajula, S., Reddy, A., Kurukulasuriya, L.R., Manrique, C., Lastra, G., Sowers, J.R. (2009). Cardiovascular Disease in Women with Diabetes. In: Tsatsoulis, A., Wyckoff, J., Brown, F. (eds) Diabetes in Women. Contemporary Diabetes. Humana Press. https://doi.org/10.1007/978-1-60327-250-6_3

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