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References
Snyder JD, Merson MH. The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bulletin of the World Health Organization 1982;60(4):605–13.
Bern C, Martines J, de Zoysa I, Glass RI. The magnitude of the global problem of diarrhoeal disease: a ten-year update. Bulletin of the World Health Organization 1992;70(6):705–14.
Victora CG, Bryce J, Fontaine O, Monasch R. Reducing deaths from diarrhoea through oral rehydration therapy. Bulletin of the World Health Organization 2000;78(10):1246–55.
Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bulletin of the World Health Organization 2003;81(3):197–204.
Thapar N, Sanderson IR. Diarrhoea in children: an interface between developing and developed countries. Lancet 2004;363(9409):641–53.
Santosham M, Keenan EM, Tulloch J, Broun D, Glass R. Oral rehydration therapy for diarrhea: an example of reverse transfer of technology. Pediatrics 1997;100(5):E10.
Zimmerman CM, Bresee JS, Parashar UD, Riggs TL, Holman RC, Glass RI. Cost of diarrhea-associated hospitalizations and outpatient visits in an insured population of young children in the United States. Pediatr Infect Dis J 2001;20(1):14–9.
Fontaine O. Zinc and treatment of diarrhoea. Med Trop (Mars) 2006;66(3):306–9.
Bines J. Intussusception and rotavirus vaccines. Vaccine 2006;24(18):3772–6.
Bines JE. Rotavirus vaccines and intussusception risk. Curr Opin Gastroenterol 2005;21(1):20–5.
Chen RT, DeStefano F. Vaccine adverse events: causal or coincidental? Lancet 1998;351(9103):611–2.
Metchnikoff E. The prolongation of life. New York: Putnam & Sons 1908.
Vergin F. Antibiotics and probiotics. Hippokrates 1954;25(4):116–9.
Lilly DM, Stillwell RH. Probiotics: growth-promoting factors produced by microorganisms. Science (New York) 1965;147:747–8.
Fuller R. Probiotics in man and animals. J Appl Bacteriol 1989;66(5):365–78.
FAO/WHO. Paper presented at Joint FAO/WHO Expert Consultation on Evaluation of Health and Nuritional Properties of Probiotics in Food including Powder Milk with Live Lactic Acid Bacteria, Cordoba, Arentina, 2001.
Reid G, Jass J, Sebulsky MT, McCormick JK. Potential uses of probiotics in clinical practice. Clin Microbiol Rev 2003;16(4):658–72.
Servin AL. Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens. FEMS Microbiol Rev 2004;28(4):405–40.
Beck C, Necheles H. Beneficial effects of administration of Lactobacillus acidophilus in diarrheal and other intestinal disorders. Am J Gastroenterol 1961;35:522–30.
Day AS. Use of complementary and alternative therapies and probiotic agents by children attending gastroenterology outpatient clinics. J Paediatr Child Health 2002;38(4):343–6.
Day AS, Whitten KE, Bohane TD. Use of complementary and alternative medicines by children and adolescents with inflammatory bowel disease. J Paediatr Child Health 2004;40(12):681–4.
Dai D, Walker WA. Protective nutrients and bacterial colonization in the immature human gut. Adv Pediatr 1999;46:353–82.
Vendt N, Grunberg H, Tuure T, et-al.. Growth during the first 6 months of life in infants using formula enriched with Lactobacillus rhamnosus GG: double-blind, randomized trial. J Hum Nutr Diet 2006;19(1):51–8.
Beno Y, He F, Hosoda M. Effect of Lactobacillus GG yoghurt on intestinal microecology in Japanese subjects. Nutr Today 1996;31(Suppl.):S9–S13.
Tannock GW, Munro K, Harmsen HJ, Welling GW, Smart J, Gopal PK. Analysis of the fecal microflora of human subjects consuming a probiotic product containing Lactobacillus rhamnosus DR20. Appl Environ Microbiol 2000;66(6):2578–88.
Michail S, Abernathy F. Lactobacillus plantarum reduces the in vitro secretory response of intestinal epithelial cells to enteropathogenic Escherichia coli infection. J Pediatr Gastroenterol Nutr 2002;35(3):350–5.
Riedel CU, Foata F, Philippe D, Adolfsson O, Eikmanns BJ, Blum S. Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-kappaB activation. World J Gastroenterol 2006;12(23):3729–35.
Alam M, Midtvedt T, Uribe A. Differential cell kinetics in the ileum and colon of germfree rats. Scand J Gastroenterol 1994;29(5):445–51.
Darmoul D, Brown D, Selsted ME, Ouellette AJ. Cryptdin gene expression in developing mouse small intestine. Am J Physiol 1997;272(1 Pt 1):G197–206.
Hooper LV, Midtvedt T, Gordon JI. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Ann Rev Nutr 2002;22:283–307.
Elmer GW, McFarland LV. Biotherapeutic agents in the treatment of infectious diarrhea. Gastroenterol Clinics North Am 2001;30(3):837–54.
Isolauri E. Probiotics in human disease. Am J Clin Nutr 2001;73(6):1142S–6S.
Walker WA, Goulet O, Morelli L, Antoine JM. Progress in the science of probiotics: from cellular microbiology and applied immunology to clinical nutrition. Europ J Nutr 2006;45 (Suppl 9):1–18.
Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI. Molecular analysis of commensal host-microbial relationships in the intestine. Science (New York) 2001;291(5505):881–4.
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004;118(2):229–41.
Neish AS, Gewirtz AT, Zeng H, et-al.. Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science (New York) 2000;289(5484):1560–3.
Kelly D, Campbell JI, King TP, et-al.. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol 2004;5(1):104–12.
Pessi T, Sutas Y, Hurme M, Isolauri E. Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy 2000;30(12):1804–8.
Pelto L, Isolauri E, Lilius EM, Nuutila J, Salminen S. Probiotic bacteria down-regulate the milk-induced inflammatory response in milk-hypersensitive subjects but have an immunostimulatory effect in healthy subjects. Clin Exp Allergy 1998;28(12):1474–9.
Majamaa H, Isolauri E. Probiotics: a novel approach in the management of food allergy. J Allergy Clin Immunol 1997;99(2):179–85.
Sutas Y, Hurme M, Isolauri E. Down-regulation of anti-CD3 antibody-induced IL-4 production by bovine caseins hydrolysed with Lactobacillus GG-derived enzymes. Scand J Immunol 1996;43(6):687–9.
Duggan C, Gannon J, Walker WA. Protective nutrients and functional foods for the gastrointestinal tract. Am J Clin Nutr 2002;75(5):789–808.
Fedorak RN, Madsen KL. Probiotics and prebiotics in gastrointestinal disorders. Curr Opin Gastroenterol 2004;20(2):146–55.
Buts JP, De Keyser N. Effects of Saccharomyces boulardii on intestinal mucosa. Dig Dis Sci 2006;51(8):1485–92.
Saavedra JM, Bauman NA, Oung I, Perman JA, Yolken RH. Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. Lancet 1994;344(8929):1046–9.
Thibault H, Aubert-Jacquin C, Goulet O. Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants. J Pediatr Gastroenterol Nutr 2004;39(2):147–52.
Chouraqui JP, Van Egroo LD, Fichot MC. Acidified milk formula supplemented with Bifidobacterium lactis : impact on infant diarrhea in residential care settings. J Pediatr Gastroenterol Nutr 2004;38(3):288–92.
Pedone CA, Arnaud CC, Postaire ER, Bouley CF, Reinert P. Multicentric study of the effect of milk fermented by Lactobacillus casei on the incidence of diarrhoea. Int J Clin Practice 2000;54(9):568–71
Szajewska H, Kotowska M, Mrukowicz JZ, Armanska M, Mikolajczyk W. Efficacy of Lactobacillus GG in prevention of nosocomial diarrhea in infants. J Pediatr 2001;138(3):361–5.
Mastretta E, Longo P, Laccisaglia A, et-al.. Effect of Lactobacillus GG and breast-feeding in the prevention of rotavirus nosocomial infection. J Pediatr Gastroenterol Nutr 2002;35(4):527–31.
Weizman Z, Asli G, Alsheikh A. Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents. Pediatrics 2005;115(1):5–9.
Agostoni C, Axelsson I, Braegger C, et-al.. Probiotic bacteria in dietetic products for infants: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2004;38(4):365–74.
Oberhelman RA, Gilman RH, Sheen P, et-al.. A placebo-controlled trial of Lactobacillus GG to prevent diarrhea in undernourished Peruvian children. J Pediatr 1999;134(1):15–20.
Hatakka K, Savilahti E, Ponka A, et-al. Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised trial. BMJ (Clin Res, Ed.) 2001;322(7298):1327.
Saran S, Gopalan S, Krishna TP. Use of fermented foods to combat stunting and failure to thrive. Nutrition (Burbank, Los Angeles County, California) 2002;18(5):393–6.
Isolauri E, Juntunen M, Rautanen T, Sillanaukee P, Koivula T. A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 1991;88(1):90–7.
Raza S, Graham SM, Allen SJ, et-al.. Lactobacillus GG in acute diarrhea. Indian Pediatr 1995;32(10):1140–2.
Guarino A, Canani RB, Spagnuolo MI, Albano F, Di Benedetto L. Oral bacterial therapy reduces the duration of symptoms and of viral excretion in children with mild diarrhea. J Pediatr Gastroenterol Nutr 1997;25(5):516–9.
Shornikova AV, Casas IA, Isolauri E, Mykkanen H, Vesikari T. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. J Pediatr Gastroenterol Nutr 1997;24(4):399–404.
Guandalini S, Pensabene L, Zikri MA, et-al.. Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial. J Pediatr Gastroenterol Nutr 2000;30(1):54–60.
Simakachorn N, Pichaipat V, Rithipornpaisarn P, Kongkaew C, Tongpradit P, Varavithya W. Clinical evaluation of the addition of lyophilized, heat-killed Lactobacillus acidophilus LB to oral rehydration therapy in the treatment of acute diarrhea in children. J Pediatr Gastroenterol Nutr 2000;30(1):68–72.
Szymanski H, Pejcz J, Jawien M, Chmielarczyk A, Strus M, Heczko PB. Treatment of acute infectious diarrhoea in infants and children with a mixture of three Lactobacillus rhamnosus strains – a randomized, double-blind, placebo-controlled trial. Aliment Pharmacol Therapeut 2006;23(2):247–53.
Höchter WCD, Hagenhoff G. Saccharomyces boulardii bei akuter Erwachsenendiarrhoe. Münch Med Wachr 1990;132:188–92.
Cetina-Sauri G, Basto.G S. Therapeutic evaluation of Saccharomyces boulardii in children with acute diarrhea. Ann Pediatr 1994;41:397–4.
Kurugol Z, Koturoglu G. Effects of Saccharomyces boulardii in children with acute diarrhoea. Acta Paediatr 2005;94(1):44–7.
Villarruel G, Rubio DM, Lopez F, et-al.. Saccharomyces boulardii in acute childhood diarrhoea: a randomized, placebo-controlled study. Acta Paediatr 2007;96(4):538–41.
Costa-Ribeiro H, Ribeiro TC, Mattos AP, et-al.. Limitations of probiotic therapy in acute, severe dehydrating diarrhea. J Pediatr Gastroenterol Nutr 2003;36(1):112–5.
Salazar-Lindo E, Miranda-Langschwager P, Campos-Sanchez M, Chea-Woo E, Sack RB. Lactobacillus casei strain GG in the treatment of infants with acute watery diarrhea: a randomized, double-blind, placebo controlled clinical trial [ISRCTN67363048]. BMC Pediatr 2004;4:18.
Khanna V, Alam S, Malik A, Malik A. Efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea. Indian J Pediatr 2005;72(11):935–8.
Kowalska-Duplaga K, Fyderek K, Szajewska H, Janiak H. Efficacy of trilack in the treatmnt of acute diarrhoea in infants and young children – a multicentre double-blind placebo-controlled study. Pediatria Wspolczesna 2004;3:295–9.
Pearce JL, Hamilton JR. Controlled trial of orally administered lactobacilli in acute infantile diarrhea. J Pediatr 1974;84(2):261–2.
Sarker SA, Sultana S, Fuchs GJ, et-al. Lactobacillus paracasei strain ST11 has no effect on rotavirus but ameliorates the outcome of nonrotavirus diarrhea in children from Bangladesh. Pediatrics 2005;116(2):e221–8.
Szajewska H, Mrukowicz JZ. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. J Pediatr Gastroenterol Nutr 2001;33 (Suppl 2):S17–25.
Van Niel CW, Feudtner C, Garrison MM, Christakis DA. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics 2002;109(4):678–84.
Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhea in children: a meta-analysis. Dig Dis Sci 2002;47(11):2625–34.
Allen SJ, Ookoko B, Martinez B, et al. Probiotics for treating infectious diarrhoea. Cockrane Database System Rev 2003(4).
Szajewska H, Skorka A, Ruszczynski M, Gieruszczak-Bialek D. Meta-analysis: Lactobacillus GG for treating acute diarrhoea in children. Aliment Pharmacol Therapy 2007;25(8):871–81.
Saxelin ME, S. Salminen,S. Vapaatalo, M. Dose response colonization of feces after oral administration of Lactobacillus casei strain GG. Microbiol Ecol Health Dis 1991;4:1–8.
De Groote MA, Frank DN, Dowell E, Glode MP, Pace NR. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatric Infect Dis J 2005;24(3):278–80.
Simon GL, Gorbach SL. Intestinal flora in health and disease. Gastroenterology 1984;86(1):174–93.
Saxelin M, Chuang NH, Chassy B, et-al.. Lactobacilli and bacteremia in southern Finland, 1989–1992. Clin Infect Dis 1996;22(3):564–6.
Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum J Clin Microbiol 1999;37(4):1227–8.
Borriello SP, Hammes WP, Holzapfel W, et-al.. Safety of probiotics that contain lactobacilli or bifido-bacteria. Clin Infect Dis 2003;36(6):775–80.
Stansbridge EM, Walker V, Hall MA, et-al.. Effects of feeding premature infants with Lactobacillus GG on gut fermentation. Arch Dis Childhood 1993;69(5 Spec No):488–92.
Cabana MD, Shane AL, Chao C, Oliva-Hemker M. Probiotics in primary care pediatrics. Clinical Pediatr 2006;45(5):405–10.
Enache-Angoulvant A, Hennequin C. Invasive Saccharomyces infection: a comprehensive review. Clin Infect Dis 2005;41(11):1559–68.
Husni RN, Gordon SM, Washington JA, Longworth DL. Lactobacillus bacteremia and endocarditis: review of 45 cases. Clin Infect Dis 1997;25(5):1048–55.
Oggioni MR, Pozzi G, Valensin PE, Galieni P, Bigazzi C. Recurrent septicemia in an immunocompro-mised patient due to probiotic strains of Bacillus subtilis. J Clin Microbiol 1998;36(1):325–6.
von Wright A. Regulating the safety of probiotics — the European approach. Curr Pharm Design 2005;11(1):17–23.
Santosham M, Nelson EA, Bresee JS. Implementing rotavirus vaccination in Asia. Vaccine 2007;25(44): 7711–6.
Glass RI, Bresee J, Jiang B, Parashar U, Yee E, Gentsch J. Rotavirus and rotavirus vaccines. Advances in experimental medicine and biology 2006;582:45–54
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Sarker, S.A., Fuchs, G.J. (2009). The Role of Probiotics in the Treatment and Prevention of Infectious Diarrhea in Children. In: Michail, S., Sherman, P.M. (eds) Probiotics in Pediatric Medicine. Nutrition and Health Series. Humana Press. https://doi.org/10.1007/978-1-60327-289-6_11
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