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Molecular Diagnostics and Cytogenetic Testing

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Neoplastic Hematopathology

Part of the book series: Contemporary Hematology ((CH))

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Abstract/Scope of Chapter

This chapter covers the basic molecular diagnostic techniques of polymerase chain reaction (PCR), quantitative PCR, reverse transcription PCR and DNA sequencing. Advantages and pitfalls in the use of these different techniques for clonality assays and chromosomal translocation detection in lymphomas and leukemias are discussed. The types of high-throughput genomic and expression array technologies are also discussed with a review of the common data analysis techniques employed to handle these techniques.

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Author information

Authors and Affiliations

  1. Department of Hematopahology, M. D. Anderson Cancer Center, The University of Texas, Houston, TX, USA

    Su Chen, Zhuang Zuo & Dan Jones

Authors
  1. Su Chen
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  2. Zhuang Zuo
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  3. Dan Jones
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Editor information

Editors and Affiliations

  1. M.D. Anderson Cancer Center, The University of Texas, Holcombe Blvd. 1515 , Houston, 77030, U.S.A.

    Dan Jones

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© 2010 Humana Press, a part of Springer Science+Business Media, LLC

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Chen, S., Zuo, Z., Jones, D. (2010). Molecular Diagnostics and Cytogenetic Testing. In: Jones, D. (eds) Neoplastic Hematopathology. Contemporary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-384-8_4

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  • DOI: https://doi.org/10.1007/978-1-60761-384-8_4

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-383-1

  • Online ISBN: 978-1-60761-384-8

  • eBook Packages: MedicineMedicine (R0)

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