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Locally Advanced Renal Cell Carcinoma

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Renal Cell Carcinoma

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

Surgery remains the standard of care for patients with localized renal cell carcinoma (RCC). However, compared to patients with low-stage, low-grade disease, patients with locally advanced RCC, including venous involvement, extracapsular extension, and involvement of adjacent lymph nodes or organs, demonstrate a high risk for both recurrence and progression of disease with decreased survival despite surgical therapy. Regardless, aggressive surgical resection, when feasible, remains the best treatment for locally advanced RCC. Although surgical management of locally advanced disease may be challenging, excellent results, including improved cancer-specific survival, can be achieved.

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Authors and Affiliations

  1. Department of Urology, University of Virginia Health System, 800422, Charlottesville, VA, 22908, USA

    Stephen H. Culp

  2. Department of Urology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1373, Houston, TX, 77030, USA

    Christopher G. Wood

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  1. Stephen H. Culp
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  2. Christopher G. Wood
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Correspondence to Christopher G. Wood .

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Editors and Affiliations

  1. Glickman Urological and Kidney Institute, Center for Urologic Oncology, Cleveland Clinic, Cleveland, 44195, Ohio, USA

    Steven C. Campbell

  2. College of Medicine, Case Western Reserve University, Cleveland Clinic Lerner, Department of Solid Tumor Oncology, Cleveland, 44195, Ohio, USA

    Brian I. Rini

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Culp, S.H., Wood, C.G. (2013). Locally Advanced Renal Cell Carcinoma. In: Campbell, S., Rini, B. (eds) Renal Cell Carcinoma. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-062-5_11

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  • DOI: https://doi.org/10.1007/978-1-62703-062-5_11

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