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Nanomedicine in Cancer

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Nanotheranostics for Cancer Applications

Part of the book series: Bioanalysis ((BIOANALYSIS,volume 5))

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Abstract

This chapter provides a broad overview of the applications of nanotechnology in cancer medicine. The fundamental physics and chemistry of different classes of nanoparticles are first described to detail the origin of their useful emergent properties in the context of current needs in cancer medicine and standard clinical practices. Specific applications focus on cancer therapeutics, cancer imaging, and in vitro diagnostics. In particular, this chapter describes how nanocrystals exhibit unique and tunable interactions with light and magnetic fields that provide new means to both detect and manipulate tumor tissue. The tunable physical structures of nanomaterials also lead to unique interactions with biomolecules, cells, and tissues that have been instrumental in precisely controlling how drugs distribute in the body and localize to solid tumors. Emphasis is given to the potential benefits of theranostic materials that pair therapeutic and diagnostic capabilities to predict and monitor the progress of therapy.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA

    Liang Ma & Andrew M. Smith

  2. Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, USA

    Liang Ma, Phuong Le & Andrew M. Smith

  3. Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA

    Phuong Le & Andrew M. Smith

  4. Department of Oncology, Mayo Clinic, Rochester, MN, USA

    Manish Kohli

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  1. Liang Ma
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  2. Phuong Le
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  3. Manish Kohli
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  4. Andrew M. Smith
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Correspondence to Andrew M. Smith .

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Editors and Affiliations

  1. Department of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA, USA

    Prakash Rai

  2. National Cancer Institute, NIH Nanodelivery Systems and Devices Branch Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, Rockville, MD, USA

    Stephanie A. Morris

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Ma, L., Le, P., Kohli, M., Smith, A.M. (2019). Nanomedicine in Cancer. In: Rai, P., Morris, S.A. (eds) Nanotheranostics for Cancer Applications. Bioanalysis, vol 5. Springer, Cham. https://doi.org/10.1007/978-3-030-01775-0_4

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