Skip to main content

Abstract

Multiple challenges exist when performing high-quality TME surgery for malignancy via the traditional “top-down” abdominal approach. Patients who are male, are obese, have a narrow pelvis, or have low, bulky tumors may present a particular challenge. The “bottom-up” approach of taTME overcomes many of these technical challenges and facilitates minimally invasive surgery. This may lead to improvements in TME quality, but long-term outcomes are not yet known. Appropriate patient selection and surgeon training are critical to ensure good outcomes with the use of taTME for patients with rectal malignancy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Heald B, Ryall RDH. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet. 1986;1(8496):1479–82.

    Google Scholar 

  2. Penna M, Cunningham C, Hompes R. Transanal total mesorectal excision: why, when, and how. Clin Colon Rectal Surg. 2017;30(5):339–45.

    Article  Google Scholar 

  3. Lacy AM, Tasende MM, Delgado S, Jimenez M, De Lacy B, Castells A. Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients. J Am Coll Surg. 2015;221(2):415–23.

    Article  Google Scholar 

  4. Motson R, Whiteford M, Hompes R, Albert M, Miles W. Current status of Trans-anal Total Mesorectal Excision (TaTME) following the second international consensus conference. Color Dis. 2015;18:13–8.

    Article  Google Scholar 

  5. Huscher C, Lirici M. Transanal total mesorectal excision: pneumodissection of retroperitoneal structures eases laparoscopic rectal resection. Dis Colon Rectum. 2017;10(60):1109–12.

    Article  Google Scholar 

  6. Ito M, Sugito M, Kobayashi A, Nishizawa Y, Tsunoda Y, Saito N. Relationship between multiple numbers of stapler firings during rectal division and anastomotic leakage after laparoscopic rectal resection. Int J Color Dis. 2008;23:703–7.

    Article  Google Scholar 

  7. Bosch SL, Nagtegaal ID. The importance of the pathologist’s role in assessment of the quality of the mesorectum. Curr Colorectal Cancer Rep. 2012;8(2):90–8.

    Article  Google Scholar 

  8. Breukink S, Pierie J, Wiggers T. Laparoscopic versus open total mesorectal excision for rectal cancer. Cochrane Database Syst Rev. 2014;15(4):CD005200.

    Google Scholar 

  9. Van der Pas MHGM, Haglind E, Cuesta MA, Fürst A, Lacy AM, Hop WCJ, et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol. 2013;14(3):210–8.

    Article  Google Scholar 

  10. Kang S, Park JW, Jeong S, Nam BH, Choi HS, Kim D, et al. Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial. Lancet Oncol. 2010;11(7):637–45.

    Article  Google Scholar 

  11. Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, et al. Short-term endpoints of conventional versus laparoscopic- assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet. 2005;365(9472):1718–26. file:///Users/reaganmaniar/Documents/Rectal cancer papers/Lap vs open/COLOR trial.pdf.

    Google Scholar 

  12. Velthuis S, Nieuwenhuis DH, Ruijter TEG, Cuesta MA. Transanal versus traditional laparoscopic total mesorectal excision for rectal carcinoma. Surg Endosc. 2014;28(12):3494–9.

    Article  Google Scholar 

  13. Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, et al. Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. J Am Med Assoc. 2017;318(16):1569–80.

    Article  Google Scholar 

  14. Stevenson A, Solomon M, Lumley J, Hewett P, Clouston A, Gebski V, et al. Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer the ALaCaRT randomized clinical trial. J Am Med Assoc. 2015;314(13):1356–63.

    Article  CAS  Google Scholar 

  15. Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M, et al. Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes. J Am Med Assoc. 2016;314(13):1346–55.

    Article  Google Scholar 

  16. Simillis C, Hompes R, Penna M, Rasheed S, Tekkis PP. A systematic review of transanal total mesorectal excision : is this the future of rectal cancer surgery? Colorectal Dis. 2016;18(1):19–36.

    Article  CAS  Google Scholar 

  17. Lacy FB. Transanal total mesorectal excision: pathological results of 186 patients with mid and low rectal cancer. Surg Endosc [Internet]. 2018;32(5):2442–7. https://doi.org/10.1007/s00464-017-5944-8.

    Article  Google Scholar 

  18. Huscher C, Lirici M. Transanal total mesorectal excision: pneumodissection of retroperitoneal structures eases laparoscopic rectal resection. Dis Colon Rectum. 2017;60:1109–12.

    Article  Google Scholar 

  19. Penna M, Hompes ÃR, Arnold ÃS, Wynn G, Austin R, Warusavitarne J, et al. Transanal total mesorectal excision international registry results of the first 720 cases. Ann Surg. 2017;266(1):111–7.

    Article  Google Scholar 

  20. Ma B, Gao P, Song Y, Zhang C, Zhang C, Wang L, et al. Transanal Total Mesorectal Excision (taTME) for rectal cancer : a systematic review and meta-analysis of oncological and perioperative outcomes compared with laparoscopic total mesorectal excision. BMC Cancer. 2016;16:380.

    Article  Google Scholar 

  21. Jiang H, Li Y, Wang B, Wang C, Liu F, Shen Z, et al. Pathological outcomes of transanal versus laparoscopic total mesorectal excision for rectal cancer : a systematic review with meta- analysis. Surg Endosc. 2018;32(6):2632–42.

    Article  Google Scholar 

  22. Mege D, Hain E, Lakkis Z, Maggiori L, Prost a la Denise J, Panis Y. Trans-anal total mesorectal excision: is it really safe and better than laparoscopic total mesorectal excision with perineal approach first in patients with low rectal cancer? A learning curve with case-matched study in 68 patients. Colorectal Dis. 2018;20(6):O143–51.

    Article  CAS  Google Scholar 

  23. Fernandez-hevia M, Delgado S, Castells A, Tasende M, Momblan D, Diaz del Gobbo G, et al. Transanal total mesorectal excision in rectal cancer: short-term outcomes in comparison with laparoscopic surgery. Ann Surg. 2015;261(2):221–7.

    Article  Google Scholar 

  24. Deijen CL, Velthuis S, Tsai A, Mavroveli S, Klerk ESMDL, Sietses C, et al. COLOR III: a multicentre randomised clinical trial comparing transanal TME versus laparoscopic TME for mid and low rectal cancer. Surg Endosc. 2016;30(8):3210–5.

    Article  Google Scholar 

  25. Lelong B, De Chaisemartin C, Meillat H, Cournier S, Boher JM, Genre D, et al. A multicentre randomised controlled trial to evaluate the efficacy, morbidity and functional outcome of endoscopic transanal proctectomy versus laparoscopic proctectomy for low-lying rectal cancer (ETAP-GRECCAR 11 TRIAL): rationale and design. BMC Cancer. 2017;17(1):253.

    Article  Google Scholar 

  26. You J, Tang R, Changchien C, Chen J, You Y, Chiang J, et al. Effect of body mass index on the outcome of patients with rectal cancer receiving curative anterior resection: disparity between the upper and lower rectum. Ann Surg. 2009;249(5):783–7.

    Article  Google Scholar 

  27. Targarona EM, Balague C, Pernas JC. Can we predict immediate outcome after laparoscopic rectal surgery? Multivariate analysis of clinical, anatomic, and pathologic features after 3-dimensional reconstruction of the pelvic anatomy. Ann Surg. 2008;247(4):642–9.

    Article  Google Scholar 

  28. Ferko A, Maly A, Orhalmi J, Dolejs J. CT/MRI pelvimetry as a useful tool when selecting patients with rectal cancer for transanal total mesorectal excision. Surg Endosc. 2016;30(3):1164–71.

    Article  Google Scholar 

  29. Rouanet P, Mourregot A, Azar CC, Carrere S, Gutowski M, Quenet F, et al. Transanal endoscopic proctectomy: an innovative procedure for difficult resection of rectal tumors in men with narrow pelvis. Dis Colon Rectum. 2013;4(56):7–9.

    Google Scholar 

  30. Killeen T, Banerjee S, Vijay V, Daren ZA, Steve F. Magnetic resonance (MR) pelvimetry as a predictor of difficulty in laparoscopic operations for rectal cancer. Surg Endosc. 2010;24:2974–9.

    Article  Google Scholar 

  31. Rectal Cancer Guidelines [Internet]. NCCN Clinical Practice Guidelines in Oncology. 2018. Available from: https://www.nccn.org/professionals/physician_gls/pdf/rectal.pdf.

  32. Smith L, Ko S, Saclarides T, Caushaj P, Orkin B, Khanuja K. Transanal endoscopic microsurgery: initial registry results. Dis Colon Rectum. 1996;39:S79–84.

    Article  CAS  Google Scholar 

  33. Piessen G, Cabral C, Benoist S, Penna C, Nordlinger B. Previous Transanal full-thickness excision increases the morbidity of radical resection for rectal cancer. Color Dis. 2012;14:445–52.

    Article  CAS  Google Scholar 

  34. Levic K, Bulut O, Hesselfeldt P, Bulow S. The outcome of rectal cancer after early salvage TME following TEM compared with primary TME: a case-matched study. Tech Coloproctol. 2012;17:397–403.

    Article  Google Scholar 

  35. Letarte F, Raval M, Karimuddin A, Phang PT, Brown CJ. Salvage TME following TEM: a possible indication for TaTME. Tech Coloproctol [Internet]. 2018;22(5):355–61. https://doi.org/10.1007/s10151-018-1784-3.

    Article  CAS  Google Scholar 

  36. Koedam TWA, Veltcamp Helbach M, Penna M, Wijsmuller A, Doornebosch P, van Westreenen H, et al. Short-term outcomes of transanal completion total mesorectal excision (cTaTME) for rectal cancer: a case-matched analysis. Surg Endosc. 2018;2:1–7.

    Google Scholar 

  37. Rullier E, Denost Q, Vendrely V, Rullier A, Ph D, Laurent C, et al. Low rectal cancer: classification and standardization of surgery. Dis Colon Rectum. 2013;5(56):560–7.

    Article  Google Scholar 

  38. Sagar S, Law P, Shaul R, Heon E, Langer J, Wright J. Hey, I just did a new operation! Ann Surg. 2015;261(1):2014–5.

    Article  Google Scholar 

  39. Mcculloch P, Feinberg J, Philippou Y, Kolias A, Kehoe S, Lancaster G, et al. Health policy progress in clinical research in surgery and IDEAL. Lancet [Internet]. 2018;6736(18):1–6. https://doi.org/10.1016/S0140-6736(18)30102-8.

    Article  Google Scholar 

  40. Barkun JS, Aronson JK, Feldman LS, Maddern GJ, Strasberg SM, Collaboration B. Surgical innovation and evaluation 1 evaluation and stages of surgical innovations. Lancet. 2009;374:1089–96.

    Article  Google Scholar 

  41. Ergina PL, Cook JA, Blazeby JM, Boutron I, Clavien P, Reeves BC, et al. Surgical innovation and evaluation 2 challenges in evaluating surgical innovation. Lancet [Internet]. 2009;374(9695):1097–104. https://doi.org/10.1016/S0140-6736(09)61086-2.

    Article  PubMed  PubMed Central  Google Scholar 

  42. OSTRiCh Transanal Total Mesorectal Excision (taTME) Registry [Internet]. OSTRiCh Consortium. Available from: http://www.ostrichconsortium.org/registry.htm#.W0YeD2Z7E_U.

  43. Mclemore EC, Harnsberger CR, Broderick RC, Leland H, Sylla P, Coker AM, et al. Transanal total mesorectal excision (taTME) for rectal cancer : a training pathway. Surg Endosc. 2016;30(9):4130–5.

    Article  Google Scholar 

  44. West NP, Morris EJ, Rotimi O, Carins A, Finan PJ, Quirke P. Pathology grading of colon cancer surgical resection and its association with survival: a retrospective observational study. Lancet Oncol. 2008;9(9):857–65.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Robertson, R.L., Brown, C.J. (2019). Indications for Malignant Neoplasia of the Rectum. In: Atallah, S. (eds) Transanal Minimally Invasive Surgery (TAMIS) and Transanal Total Mesorectal Excision (taTME). Springer, Cham. https://doi.org/10.1007/978-3-030-11572-2_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-11572-2_19

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11571-5

  • Online ISBN: 978-3-030-11572-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics