Skip to main content

Proposal of Electrode System for Measuring Level of Glucose in the Blood

  • Conference paper
  • First Online:
AETA 2018 - Recent Advances in Electrical Engineering and Related Sciences: Theory and Application (AETA 2018)

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 554))

  • 1110 Accesses

Abstract

The paper describes the development of electrode system and blood glucose measuring circuit for glucose analysis. Measuring blood glucose levels is today one of the standards of medical procedures that determine the physiological state of a person. The task of the work was to implement the measuring system, to test the functionality of the whole system, the measurement tests were carried out and the measured data were subsequently processed statistically. In designing and constructing the electrode system, the resistive principle of measurement of non-electrical quantities was applied because the system focuses on the measurement of the concentration of a certain substance in the liquid. These are electrolytic sensors using gold electrodes. The part that deals with the construction of the electrical measuring circuit has determined the conditions that the circuit must meet. For this reason, a micro-ammeter was designed to provide the source voltage, measure the current and convert it back to a suitable magnitude. The current measured by the circuit is proportional to the concentration of glucose in the solution. Glucose oxidase enzyme was used to distinguish glucose molecules in the blood and determine its concentration, which, together with the supply of the required voltage, provides useful chemical reactions. Based on the processed data, it is possible to evaluate the constructed system and lay the foundations for further development of the issue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Comeaux, R., Novotny, P.: Biosensors: Properties, Materials and Applications. Biotechnology in Agriculture, Industry and Medicine Series. Nova Science Publishers, New York (2009). ISBN 978-1-60741-617-3

    Google Scholar 

  2. Clarke, S.F., Foster, J.R.: A history of blood glucose meters and their role in self-monitoring of diabetes mellitus. Br. J. Biomed. Sci. 69(2), 83 (2012)

    Article  Google Scholar 

  3. Chang, T.M.S.: Biomedical Applications of Immobilized Enzymes and Proteins. Springer Science & Business Media (2013)

    Google Scholar 

  4. Holzinger, U., et al.: Real-time continuous glucose monitoring in critically ill patients: a prospective randomized trial. Diabetes care 33(3), 467–472 (2010)

    Google Scholar 

  5. Pickup, J.C., ed.: Insulin Pump Therapy and Continuous Glucose Monitoring. Oxford University Press, Oxford (2009). ISBN 978-0-19-956860-4

    Google Scholar 

  6. Eggins, B.R.: Chemical Sensors and Biosensors. Wiley, Chichester (2002). ISBN 0-471-89913-5

    Google Scholar 

  7. Hermanson, G.T.: Bioconjugate Techniques, 2nd edn. Academic Press, San Diego (2008). ISBN 978-0-12-370501-3

    Google Scholar 

  8. Bugg, T.D.H.: Introduction to Enzyme and Coenzyme Chemistry, 3rd ed. Wiley, Hoboken (2013). ISBN 9781118348994

    Google Scholar 

  9. Langendam, M., et al.: Continuous glucose monitoring systems for type 1 diabetes mellitus. The Cochrane Library (2012)

    Google Scholar 

  10. Rodbard, D.: Continuous glucose monitoring: a review of successes, challenges, and opportunities. Diab. Technol. Ther. 18(S2), S2-3–S2-13 (2016)

    Google Scholar 

  11. Nichols, S.P., et al.: Biocompatible materials for continuous glucose monitoring devices. Chem. Rev. 113(4), 2528–2549 (2013)

    Google Scholar 

  12. Wagner, J., Tennen, H., Wolpert, H.: Continuous glucose monitoring: a review for behavioral researchers. Psychosom. Med. 74(4), 356 (2012)

    Google Scholar 

  13. English, B.P., et al.: Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited. Nat. Chem. Biol. 2(2), 87–94 (2006)

    Google Scholar 

  14. Purich, D.L.: Enzyme Kinetics: Catalysis & Control: A Reference of Theory and Best-Practice Methods. Elsevier/Academic Press, Amsterdam (2010). ISBN 9780123809247

    Google Scholar 

  15. Fiedorová, K.: Návrh elektrody pro měření koncentrace glukózy v krvi. Ostrava. Dostupné z: http://hdl.handle.net/10084/119180. Diplomová práce. Vysoká škola báňská - Technická univerzita Ostrava (2017). [cit. 2018-06-25]

Download references

Acknowledgment

The work and the contributions were supported by the project SV4508811/2101 ‘Bi- medicínské inženýrské systémy XIV’. This study was supported by the research project The Czech Science Foundation (GACR) 2017 No. 15330/16/AGR Investment evaluation of medical device development run at the Faculty of Informatics and Management, University of Hradec Kralove, Czech Republic. This study was supported by the research project The Czech Science Foundation (TACR) ETA No. TL01000302 Medical devices development as an effective investment for public and private entities.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Klara Fiedorova .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Fiedorova, K., Augustynek, M. (2020). Proposal of Electrode System for Measuring Level of Glucose in the Blood. In: Zelinka, I., Brandstetter, P., Trong Dao, T., Hoang Duy, V., Kim, S. (eds) AETA 2018 - Recent Advances in Electrical Engineering and Related Sciences: Theory and Application. AETA 2018. Lecture Notes in Electrical Engineering, vol 554. Springer, Cham. https://doi.org/10.1007/978-3-030-14907-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-14907-9_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-14906-2

  • Online ISBN: 978-3-030-14907-9

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics