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The Value of Sleep for Optimizing Health

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Nutrition, Fitness, and Mindfulness

Part of the book series: Nutrition and Health ((NH))

Abstract

We spend a third of our lives sleeping, a behavioral state that typically requires the person to lie recumbent in the dark with eyes closed, in a comfortable, quiet, and safe location. If evolutionary processes, spanning millions of years, are responsible for fine-tuning our adaptive advantage, then it stands to reason that sleep must be an evolved adaptation important for the survival (and health) of all mammalian species. Since the 1950s, when the different stages of sleep were first identified, enormous intellectual and physical resources have been dedicated to the task of identifying a function (or set of functions) for sleep and to better understand why sleep is so important for general health. Prominent among the many scientific hypotheses of sleep function are whether (and how) sleep serves a basic restorative function, a memory/cognition function, and/or a general health function. In contrast to these health-oriented hypotheses of sleep function is the reality that lost and disrupted sleep promote their own set of negative health outcomes. This chapter will describe what is known about healthy sleep, disrupted sleep, and sleep loss and their general effects on cognitive and physical health. An efficient, practical clinical assessment of sleep quality and quantity and the approach to sleep interventions are also described.

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References

  1. Almeida CM, Malheiro A. Sleep, immunity and shift workers: a review. Sleep Sci. 2016;9(3):164–8.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Banks S, Dinges DF. Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med. 2007;3(5):519–28.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Baum KT, Desai A, et al. Sleep restriction worsens mood and emotion regulation in adolescents. J Child Psychol Psychiatry. 2014;55(2):180–90.

    Article  PubMed  Google Scholar 

  4. Bent S, Padula A, et al. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006;119(12):1005–12.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Berger RJ, Phillips NH. Energy conservation and sleep. Behav Brain Res. 1995;69(1–2):65–73.

    Article  CAS  PubMed  Google Scholar 

  6. Bliwise DL. Sleep in normal aging and dementia. Sleep. 1993;16(1):40–81.

    Article  CAS  PubMed  Google Scholar 

  7. Broussard JL, Kilkus JM, et al. Elevated ghrelin predicts food intake during experimental sleep restriction. Obesity (Silver Spring). 2016a;24(1):132–8.

    Article  CAS  Google Scholar 

  8. Broussard JL, Wroblewski K, et al. Two nights of recovery sleep reverses the effects of short-term sleep restriction on diabetes risk. Diabetes Care. 2016b;39(3):e40–1.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Burgess HJ, Sharkey KM, Eastman CI. Bright light, dark, and melatonin can promote circadian adaptation in night shift workers. Sleep Med Rev. 2002;6:407–20.

    Article  PubMed  Google Scholar 

  10. Buysse DJ, Reynolds CF 3rd, et al. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213.

    Article  CAS  PubMed  Google Scholar 

  11. Buzsaki G. The hippocampo-neocortical dialogue. Cereb Cortex. 1996;6(2):81–92.

    Article  CAS  PubMed  Google Scholar 

  12. Cajochen C, Krauchi K, et al. Role of melatonin in the regulation of human circadian rhythms and sleep. J Neuroendocrinol. 2003;15(4):432–7.

    Article  CAS  PubMed  Google Scholar 

  13. Corkin S. What’s new with the amnesic patient H.M.? Nat Rev Neurosci. 2002;3(2):153–60.

    Article  CAS  PubMed  Google Scholar 

  14. Cunnington D. Non-benzodiazepine hypnotics: do they work for insomnia? BMJ. 2012;346:e8699.

    Article  PubMed  CAS  Google Scholar 

  15. Daley C, McNiel DE, et al. “I did what?” Zolpidem and the courts. J Am Acad Psychiatry Law. 2011;39(4):535–42.

    PubMed  Google Scholar 

  16. Dement W. The effect of dream deprivation. Science. 1960;131(3415):1705–7.

    Article  CAS  PubMed  Google Scholar 

  17. Diekelmann S, Wilhelm I, et al. The whats and whens of sleep-dependent memory consolidation. Sleep Med Rev. 2009;13(5):309–21.

    Article  PubMed  Google Scholar 

  18. Drager LF, McEvoy RD, et al. Sleep apnea and cardiovascular disease: lessons from recent trials and need for team science. Circulation. 2017;136(19):1840–50.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Duffy JF, Willson HJ, et al. Healthy older adults better tolerate sleep deprivation than young adults. J Am Geriatr Soc. 2009;57(7):1245–51.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Dumoulin Bridi MC, Aton SJ, et al. Rapid eye movement sleep promotes cortical plasticity in the developing brain. Sci Adv. 2015;1(6):e1500105.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  21. Dworak M, McCarley RW, et al. Sleep and brain energy levels: ATP changes during sleep. J Neurosci. 2010;30(26):9007–16.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Endo T, Schwierin B, et al. Selective and total sleep deprivation: effect on the sleep EEG in the rat. Psychiatry Res. 1997;66(2–3):97–110.

    Article  CAS  PubMed  Google Scholar 

  23. Eriksen CA, Gillberg M, et al. Sleepiness and sleep in a simulated “six hours on/six hours off” sea watch system. Chronobiol Int. 2006;23(6):1193–202.

    Article  PubMed  Google Scholar 

  24. Fitzgerald MP, Litman HJ, et al. The association of nocturia with cardiac disease, diabetes, body mass index, age and diuretic use: results from the BACH survey. J Urol. 2007;177(4):1385–9.

    Article  PubMed  Google Scholar 

  25. Fogel SM, Smith CT. The function of the sleep spindle: a physiological index of intelligence and a mechanism for sleep-dependent memory consolidation. Neurosci Biobehav Rev. 2011;35(5):1154–65.

    Article  PubMed  Google Scholar 

  26. Frank MG. Sleep and developmental plasticity not just for kids. Prog Brain Res. 2011;193:221–32.

    Article  PubMed  Google Scholar 

  27. Hasselmo ME. Neuromodulation: acetylcholine and memory consolidation. Trends Cogn Sci. 1999;3(9):351–9.

    Article  CAS  PubMed  Google Scholar 

  28. Hedner J, Yaeche R, et al. Zaleplon shortens subjective sleep latency and improves subjective sleep quality in elderly patients with insomnia. The Zaleplon Clinical Investigator Study Group. Int J Geriatr Psychiatry. 2000;15(8):704–12.

    Article  CAS  PubMed  Google Scholar 

  29. Huedo-Medina TB, Kirsch I, et al. Effectiveness of non-benzodiazepine hypnotics in treatment of adult insomnia: meta-analysis of data submitted to the Food and Drug Administration. BMJ. 2012;345:e8343.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  30. Ibarra-Coronado EG, Pantaleon-Martinez AM, et al. The bidirectional relationship between sleep and immunity against infections. J Immunol Res. 2015;2015:678164.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  31. Irish LA, Kline CE, et al. The role of sleep hygiene in promoting public health: a review of empirical evidence. Sleep Med Rev. 2015;22:23–36.

    Article  PubMed  Google Scholar 

  32. Irwin MR. Why sleep is important for health: a psychoneuroimmunology perspective. Annu Rev Psychol. 2015;66:143–72.

    Article  PubMed  Google Scholar 

  33. Irwin MR, Opp MR. Sleep health: reciprocal regulation of sleep and innate immunity. Neuropsychopharmacology. 2017;42(1):129–55.

    Article  CAS  PubMed  Google Scholar 

  34. Jacobs BP, Bent S, et al. An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomnia. Medicine (Baltimore). 2005;84(4):197–207.

    Article  Google Scholar 

  35. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–5.

    Article  CAS  PubMed  Google Scholar 

  36. Khalsa SB, Jewett ME, et al. A phase response curve to single bright light pulses in human subjects. J Physiol. 2003;549(Pt 3):945–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Knutson KL. Impact of sleep and sleep loss on glucose homeostasis and appetite regulation. Sleep Med Clin. 2007;2(2):187–97.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Krause AJ, Simon EB, et al. The sleep-deprived human brain. Nat Rev Neurosci. 2017;18(7):404–18.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Kushida CA, Bergmann BM, et al. Sleep deprivation in the rat: IV. Paradoxical sleep deprivation. Sleep. 1989;12(1):22–30.

    Article  CAS  PubMed  Google Scholar 

  40. Lee AK, Wilson MA. Memory of sequential experience in the hippocampus during slow wave sleep. Neuron. 2002;36(6):1183–94.

    Article  CAS  PubMed  Google Scholar 

  41. Li W, Ma L, et al. REM sleep selectively prunes and maintains new synapses in development and learning. Nat Neurosci. 2017;20(3):427–37.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Lo JC, Ong JL, et al. Cognitive performance, sleepiness, and mood in partially sleep deprived adolescents: the need for sleep study. Sleep. 2016;39(3):687–98.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Mander BA, Winer JR, et al. Sleep and human aging. Neuron. 2017;94(1):19–36.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Marks GA, Shaffery JP, et al. A functional role for REM sleep in brain maturation. Behav Brain Res. 1995;69(1–2):1–11.

    Article  CAS  PubMed  Google Scholar 

  45. Morgenstern M, Wang J, et al. Obstructive sleep apnea: an unexpected cause of insulin resistance and diabetes. Endocrinol Metab Clin North Am. 2014;43(1):187–204.

    Article  PubMed  Google Scholar 

  46. Morgenthaler TI, Hashmi S, et al. High school start times and the impact on high school students: what we know, and what we hope to learn. J Clin Sleep Med. 2016;12(12):1681–9.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Nishida M, Pearsall J, et al. REM sleep, prefrontal theta, and the consolidation of human emotional memory. Cereb Cortex. 2009;19(5):1158–66.

    Article  PubMed  Google Scholar 

  48. Plihal W, Born J. Effects of early and late nocturnal sleep on declarative and procedural memory. J Cogn Neurosci. 1997;9(4):534–47.

    Article  CAS  PubMed  Google Scholar 

  49. Porcu S, Casagrande M, et al. Sleep and alertness during alternating monophasic and polyphasic rest-activity cycles. Int J Neurosci. 1998;95(1–2):43–50.

    Article  CAS  PubMed  Google Scholar 

  50. Rajan P, Greenberg H. Obstructive sleep apnea as a risk factor for type 2 diabetes mellitus. Nat Sci Sleep. 2015;7:113–25.

    PubMed  PubMed Central  Google Scholar 

  51. Rechtschaffen A. Current perspectives on the function of sleep. Perspect Biol Med. 1998;41(3):359–90.

    Article  CAS  PubMed  Google Scholar 

  52. Rechtschaffen A, Bergmann BM, et al. Sleep deprivation in the rat: X. Integration and discussion of the findings. 1989. Sleep. 2002;25(1):68–87.

    Article  PubMed  Google Scholar 

  53. Reynolds AC, Banks S. Total sleep deprivation, chronic sleep restriction and sleep disruption. Prog Brain Res. 2010;185:91–103.

    Article  PubMed  Google Scholar 

  54. Roffwarg HP, Muzio JN, et al. Ontogenetic development of the human sleep-dream cycle. Science. 1966;152(3722):604–19.

    Article  CAS  PubMed  Google Scholar 

  55. Schmid SM, Hallschmid M, et al. The metabolic burden of sleep loss. Lancet Diabetes Endocrinol. 2015;3(1):52–62.

    Article  CAS  PubMed  Google Scholar 

  56. Schrimpf M, Liegl G, et al. The effect of sleep deprivation on pain perception in healthy subjects: a meta-analysis. Sleep Med. 2015;16(11):1313–20.

    Article  PubMed  Google Scholar 

  57. Scoville WB, Milner B. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry. 1957;20(1):11–21.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  58. Shapiro CM, Goll CC, et al. Heat production during sleep. J Appl Physiol Respir Environ Exerc Physiol. 1984;56(3):671–7.

    CAS  PubMed  Google Scholar 

  59. Spiegel K, Knutson K, et al. Sleep loss: a novel risk factor for insulin resistance and type 2 diabetes. J Appl Physiol (1985). 2005;99(5):2008–19.

    Article  CAS  Google Scholar 

  60. Stepanski EJ, Wyatt JK. Use of sleep hygiene in the treatment of insomnia. Sleep Med Rev. 2003;7(3):215–25.

    Article  PubMed  Google Scholar 

  61. Taheri S, Lin L, et al. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  62. Tononi G, Cirelli C. Sleep function and synaptic homeostasis. Sleep Med Rev. 2006;10(1):49–62.

    Article  PubMed  Google Scholar 

  63. Urry E, Landolt HP. Adenosine, caffeine, and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics. Curr Top Behav Neurosci. 2015;25:331–66.

    Article  PubMed  Google Scholar 

  64. van Cauter E, Leproult R, et al. Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men. JAMA. 2000;284(7):861–8.

    Article  PubMed  Google Scholar 

  65. van Cauter E, Holmback U, et al. Impact of sleep and sleep loss on neuroendocrine and metabolic function. Horm Res. 2007;67(Suppl 1):2–9.

    PubMed  Google Scholar 

  66. van der Helm E, Walker MP. Sleep and emotional memory processing. Sleep Med Clin. 2011;6(1):31–43.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Walker MP, Brakefield T, et al. Practice with sleep makes perfect: sleep-dependent motor skill learning. Neuron. 2002;35(1):205–11.

    Article  CAS  PubMed  Google Scholar 

  68. Williamson AM, Feyer AM. Moderate sleep deprivation produces impairments in cognitive and motor performance equivalent to legally prescribed levels of alcohol intoxication. Occup Environ Med. 2000;57(10):649–55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Yurcheshen M, Seehuus M, et al. Updates on nutraceutical sleep therapeutics and investigational research. Evid Based Complement Alternat Med. 2015;2015:105256.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Zepelin H. Mammalian sleep. In: Kryger R, Dement WC, editors. Principles and practice of sleep medicine. Philadelphia: W.B. Saunders Company; 2000. p. 82–92.

    Google Scholar 

  71. Zhang XM, Shi J, et al. The effect of obstructive sleep apnea syndrome on growth and development in nonobese children: a parallel study of twins. J Pediatr. 2015;166(3):646–50 e641.

    Article  PubMed  Google Scholar 

  72. Zielinski MR, McKenna JT, et al. Functions and mechanisms of sleep. AIMS Neurosci. 2016;3(1):67–104.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Biomedical Sciences, University of South Carolina School of Medicine, Greenville, Greenville, SC, USA

    Matthew A. Tucker

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  1. Matthew A. Tucker
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Correspondence to Matthew A. Tucker .

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Editors and Affiliations

  1. Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Jaime Uribarri

  2. The National Kidney Foundation, Inc., New York, NY, USA

    Joseph A. Vassalotti

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Tucker, M.A. (2020). The Value of Sleep for Optimizing Health. In: Uribarri, J., Vassalotti, J. (eds) Nutrition, Fitness, and Mindfulness. Nutrition and Health. Humana, Cham. https://doi.org/10.1007/978-3-030-30892-6_14

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  • DOI: https://doi.org/10.1007/978-3-030-30892-6_14

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