Abstract
The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.
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Acknowledgments
The authors are grateful for revision of this manuscript by Andrea Hope. This work was supported in part by JSPS KAKENHI Grant Number 16 K16487 to Shun Takagi.
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Takagi, S., Kime, R., Midorikawa, T., Niwayama, M., Sakamoto, S., Katsumura, T. (2020). Differences in Muscle O2 Dynamics During Treadmill Exercise Between Aerobic Capacity-Matched Overweight and Normal-Weight Adults. In: Ryu, PD., LaManna, J., Harrison, D., Lee, SS. (eds) Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology, vol 1232. Springer, Cham. https://doi.org/10.1007/978-3-030-34461-0_28
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DOI: https://doi.org/10.1007/978-3-030-34461-0_28
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