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Characterising Contrast Agents for Magnetic Resonance Imaging

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Abstract

In Magnetic Resonance Imaging (MRI), complexes of Gd3+ are very often used as contrast agents to locally accelerate relaxation of water protons. The theoretical models developed to quantitatively describe this phenomenon involve parameters which determine the spin-lattice relaxation for the complexes. Their values can be obtained by simulating a series of EPR spectra recorded at different frequencies over a range of temperatures. These studies reveal the factors determining the efficacy of the complexes and can be used to optimise their structure.

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Author information

Authors and Affiliations

  1. Interdisciplinary Laboratory of Physics, Grenoble Alpes University, Grenoble, France

    E. Belorizky

  2. Ionic Recognition and Coordination Chemistry, Inorganic and Biological Chemistry, UMR-E3, Grenoble Alpes University, Grenoble, France

    P. H. Fries

Authors
  1. E. Belorizky
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  2. P. H. Fries
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Belorizky, E., Fries, P.H. (2020). Characterising Contrast Agents for Magnetic Resonance Imaging. In: Electron Paramagnetic Resonance Spectroscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-39668-8_11

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