Abstract
Brain glioma segmentation using multi-parametric magnetic resonance (MR) imaging has significant clinical value. Although 3D convolutional neural networks (CNNs) have become increasingly prevalent in delivering this segmentation task, these models still suffer from an insufficient ability to high-resolution feature representation for small and irregular regions, limited local receptive fields, and poor long-range dependencies. In this paper, we propose a 3D High-resolution and Non-local Feature Network (HNF-Net) for brain glioma segmentation using multi-parametric MR imaging. We construct HNF-Net based mainly on the parallel multi-scale fusion (PMF) module, which helps produce strong high-resolution feature representation and aggregate multi-scale contextual information. We also introduce the expectation-maximization attention (EMA) module to HNF-Net, aiming to capture the long-range dependent contextual information and reduce the feature redundancy in a lightweight fashion. We evaluated our HNF-Net on the BraTS 2019 Challenge dataset against eight top-ranking methods listed on the challenge leaderboard. Our results suggest that the proposed HNF-Net achieves improved overall performance over these methods, and our ablation study demonstrates the effectiveness of the PMF module and EMA module.
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Acknowledgement
Haozhe Jia and Yong Xia were partially supported by the Science, Technology and Innovation Commission of Shenzhen Municipality, China under Grant JCYJ20180306171334997, the National Natural Science Foundation of China under Grant 61771397, and the Innovation Foundation for Doctor Dissertation of Northwestern Polytechnical University under Grant CX202042.
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Jia, H., Xia, Y., Cai, W., Huang, H. (2020). Learning High-Resolution and Efficient Non-local Features for Brain Glioma Segmentation in MR Images. In: Martel, A.L., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020. Lecture Notes in Computer Science(), vol 12264. Springer, Cham. https://doi.org/10.1007/978-3-030-59719-1_47
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