Abstract
Treatment of adults with medulloblastoma is largely based on data regarding the treatment of children. Craniospinal irradiation remains the cornerstone of therapy followed by adjuvant chemotherapy. Concurrent chemotherapy is sometimes used as well, but this remains controversial with the biggest concern of depressed blood counts given the amount of bone marrow irradiated. Overall, given the large volume irradiated, more advanced techniques such as proton therapy, tomotherapy, or IMRT have been utilized to decrease acute and late effects of treatment. Given this, specific contouring guidelines are important to include the cribriform plate and other foramina that contain cerebrospinal fluid (CSF) with more targeted plans. In the 3D conformal era for craniospinal irradiation, these areas were automatically included in the fields. This chapter describes specific directions for inclusion of all areas of CSF and planning pearls.
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Cho, C.J., Halasz, L.M. (2021). Adult Medulloblastoma. In: Halasz, L.M., Lo, S.S., Chang, E.L., Sahgal, A. (eds) Intracranial and Spinal Radiotherapy . Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-64508-3_18
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DOI: https://doi.org/10.1007/978-3-030-64508-3_18
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