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ER-to-Golgi transport

  • Chapter
The Golgi Apparatus

Abstract

Biosynthetic cargo enters the secretory pathway at the endoplasmic reticu-lum (ER) where it is properly folded before it becomes sorted and concentrated into transport carriers that move towards the Golgi complex. The basic protein machinery involved in bidirectional transport between the ER and the Golgi complex has long been identified and is fairly well characterized (Lee et al. 2004). The vesicular coat complex COPII mediates ER exit, while retrograde transport from the Golgi complex to the ER involves the function of the vesicular coat complex COPI. In the following paragraphs we focus on our current knowledge on the spatial and temporal organization of ER-to-Golgi transport at the molecular level.

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Author information

Authors and Affiliations

  1. Cell Biology Cell Biophysics Unit, EMBL, Meyerhofstraße 1, 69117, Heidelberg, Germany

    Fatima Verissimo

  2. Cell Biology Cell Biophysics Unit, EMBL, Meyerhofstraße 1, 69117, Heidelberg, Germany

    Rainer Pepperkok

Authors
  1. Fatima Verissimo
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  2. Rainer Pepperkok
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Editor information

Editors and Affiliations

  1. Department of Cell Biology and Oncology, Consorzio Mario Negri Sud Laboratory of Intracellular Traffic, S. Maria Imbaro (Chieti), Italy

    Alexander A. Mironov

  2. Department of Cell Biology and Ultrastructure Research Institute of Histology and Embryology Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

    Margit Pavelka

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© 2008 Springer-Verlag/Wien

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Verissimo, F., Pepperkok, R. (2008). ER-to-Golgi transport. In: Mironov, A.A., Pavelka, M. (eds) The Golgi Apparatus. Springer, Vienna. https://doi.org/10.1007/978-3-211-76310-0_20

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