Abstract
Those undergoing hematopoietic stem cell transplant and related treatment are at risk for significant deconditioning and loss of overall functional abilities. The use of physical activity, in the form of both aerobic and strengthening, has been shown to be effective in the prevention and remediation of loss of strength, cancer-related fatigue, loss of cognitive functioning, and decreased quality of life. Rehabilitation services, primarily occupational and physical therapies, are beneficial members of the treatment team and are able to assist with return of function using a variety of techniques including engagement in physical activity.
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The side effects associated with high-dose chemotherapy and HSCT may result in physical debilitation. The incorporation of physical activity has been shown to minimize the loss of strength, independence, energy, and quality of life. Although the majority of research has been performed on limited sample sizes, it can be inferred by the multitude of studies across the spectrum of cancer diagnoses that physical activity is likely to be beneficial for the HSCT population.
An optimal exercise program has not been defined; however, it has been shown that moderate aerobic activity along with a strengthening routine may help prevent steroid myopathy and improve cancer-related fatigue quality of life.
Occupational and physical therapists are essential members of the HSCT treatment team who provide recommendations on the implementation of physical activity, as well as assist with prevention, remediation, and compensation of the complications associated with treatment.
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Pidkowicz, J. (2015). Physical and Occupational Therapy. In: Maziarz, R., Slater, S. (eds) Blood and Marrow Transplant Handbook. Springer, Cham. https://doi.org/10.1007/978-3-319-13832-9_8
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DOI: https://doi.org/10.1007/978-3-319-13832-9_8
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