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Comparative Cardiac Anatomy

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Handbook of Cardiac Anatomy, Physiology, and Devices

Abstract

The need for appropriate animal models to conduct translational research is vital for advancements in the diagnosis and treatment of heart disease. The choice of animal model to be employed must be critically evaluated. In this chapter, we present the comparative cardiac anatomies of several of the commonly employed animal models for preclinical research (dog, pig, and sheep). General comparisons focus on several specific anatomical features: the atria, ventricles, valves, coronary system, lymphatics, and the conduction system. Finally, we present novel qualitative and quantitative data obtained from perfusion-fixed specimens of these commonly used animal models.

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Authors and Affiliations

  1. Department of Surgery, University of Minnesota, 420 Delaware St. SE, B 172 Mayo, MMC 107, Minneapolis, MN, 55455, USA

    Alexander J. Hill PhD & Paul A. Iaizzo PhD

  2. Medtronic, 8200 Coral Sea Street NE, Mounds View, Minneapolis, MN, 55112, USA

    Alexander J. Hill PhD

Authors
  1. Alexander J. Hill PhD
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  2. Paul A. Iaizzo PhD
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Correspondence to Paul A. Iaizzo PhD .

Editor information

Editors and Affiliations

  1. B172 Mayo, MMC 195, University of Minnesota Department of Surgery, Minneapolis, Minnesota, USA

    Paul A. Iaizzo

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Hill, A.J., Iaizzo, P.A. (2015). Comparative Cardiac Anatomy. In: Iaizzo, P. (eds) Handbook of Cardiac Anatomy, Physiology, and Devices. Springer, Cham. https://doi.org/10.1007/978-3-319-19464-6_6

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