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Acetogenins from Annonaceae

  • Chapter
Progress in the Chemistry of Organic Natural Products 101

Part of the book series: Progress in the Chemistry of Organic Natural Products ((POGRCHEM,volume 101))

Abstract

In recent decades, annonaceous acetogenins have become highly studied plant secondary metabolites in terms of their isolation, structure elucidation, synthesis, biological evaluation, mechanism of action, and toxicity. The aim of the present contribution is to summarize chemical and biological reports published since 1997 on annonaceous acetogenins and synthetic acetogenin mimics. The compounds are considered biologically in terms of their cytotoxicity for cancer cell lines, neurotoxicity, pesticidal effects, and miscellaneous activities.

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Acknowledgments

This work was supported by grants from the Ministry of Science and Technology (National Science Council) of Taiwan NSC100-2320-B-110-001-MY2 awarded to C.C.L., MOST 103-2320-B-037-005-MY2 & 102-2628-B-037-003-MY3 awarded to F.R.C., and NSC 103-2911-I-002-303, NSC101-2632-B039-001-MY3, NSC100-2320-B-110-001-MY2 National Health Research Institutes NHRI-EX102-10241BI, and CMU under the Aim for Top University Plan of the Ministry of Education, Taiwan award to Y.C.W. as well as the Excellence for Cancer Research Center Grant, the Ministry of Health and Welfare, Executive Yuan, Taipei, Taiwan (MOHW104-TDU-B-212-124-003) and the grant for Health and Welfare Surcharge of Tobacco Products.

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Authors and Affiliations

  1. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, 804, Taiwan

    Chih-Chuang Liaw

  2. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, 807, Taiwan

    Jing-Ru Liou, Tung-Ying Wu & Fang-Rong Chang

  3. School of Pharmacy, College of Pharmacy, China Medical University, Taichung, 404, Taiwan

    Yang-Chang Wu

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  1. Div. Medicinal Chemistry & Pharmacognosy, The Ohio State University College of Pharmacy, Columbus, Ohio, USA

    A. Douglas Kinghorn

  2. Linz, Austria

    Heinz Falk

  3. Department of Pharmaceutical and Biological Chemistry, UCL School of Pharmacy, London, United Kingdom

    Simon Gibbons

  4. Graduate School of Pharmaceutical Scienc, Hokkaido University, Sapporo, Japan

    Jun'ichi Kobayashi

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Liaw, CC., Liou, JR., Wu, TY., Chang, FR., Wu, YC. (2016). Acetogenins from Annonaceae. In: Kinghorn, A., Falk, H., Gibbons, S., Kobayashi, J. (eds) Progress in the Chemistry of Organic Natural Products 101. Progress in the Chemistry of Organic Natural Products, vol 101. Springer, Cham. https://doi.org/10.1007/978-3-319-22692-7_2

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