Abstract
The epidemiology, risk factors, and biological basis of suicidal behaviors have been the object of an ever-increasing research in the last three decades. During this period, researchers all over the world have identified potential biomarkers of risk and developed several theories about the mechanisms leading to suicidal behavior. However, the lack of common terminology, instruments, and cooperation has been a major deterrent. Today, the community has established the bases for this collaboration and evidence coming from neuroscientific studies can already be applied to the field of suicidology. We present here a potential semiology based on current evidence coming from biological, clinical, and neuroimaging studies.
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References
American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing, Arlington
Anestis MD, Soberay KA, Gutierrez PM et al (2014) Reconsidering the link between impulsivity and suicidal behavior. Pers Soc Psychol Rev 18:366–386. doi:10.1177/1088868314535988
Åsberg M, Träskman L, Thorén P (1976) 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Arch Gen Psychiatry 33:1193–1197
Baca-García E, Diaz Sastre C, García Resa E et al (2004) Suicide attempts and impulsivity. Eur Arch Psychiatry Clin Neurosci 255:152–156. doi:10.1007/s00406-004-0549-3
Bolton JM (2015) Suicide risk assessment in the emergency department: out of the darkness. Depress Anxiety 32:73–75. doi:10.1002/da.22320
Carli V, Hoven CW, Wasserman C et al (2014) A newly identified group of adolescents at “invisible” risk for psychopathology and suicidal behavior: findings from the SEYLE study. World Psychiatry 13:78–86. doi:10.1002/wps.20088
Courtet P, Gottesman II, Jollant F, Gould TD (2011) The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies? 1:e7. doi: 10.1038/tp.2011.6
Courtet P, Jaussent I, López-Castromán J, Gorwood P (2014) Poor response to antidepressants predicts new suicidal ideas and behavior in depressed outpatients. Eur Neuropsychopharmacol 24:1650–1658. doi:10.1016/j.euroneuro.2014.07.007
Durkheim E (1897) Suicide: A study in sociology. Free Press, New York
Dana Lizardi PD, Barbara Stanley PD (2010) Treatment engagement: a neglected aspect in the psychiatric care of suicidal patients. Psychiatr Serv, doi: 10.1176/ps.2010.61.issue-12;website:website:ps-site;article:article:10.1176/ps.2010.61.12.1183;pageGroup:string:Publication
Ducasse D, René E, Béziat S et al (2014) Acceptance and commitment therapy for management of suicidal patients: a pilot study. Psychother Psychosom 83:374–376. doi:10.1159/000365974
Fergusson DM, Beautrais AL, Horwood LJ (2003) Vulnerability and resiliency to suicidal behaviours in young people. Psychol Med 33:61–73
Giner L, Jaussent I, Olie E et al (2014) Violent and serious suicide attempters. J Clin Psychiatry 75:e191–e197. doi:10.4088/JCP.13m08524
Gipson PY, Agarwala P, Opperman KJ et al (2015) Columbia-suicide severity rating scale: predictive validity with adolescent psychiatric emergency patients. Pediatr Emerg Care 31:88–94. doi:10.1097/PEC.0000000000000225
Hunt IM, KAPUR N, WEBB R et al (2009) Suicide in recently discharged psychiatric patients: a case-control study. Psychol Med 39:443–449. doi:10.1017/S0033291708003644
Husky M, Olie E, Guillaume S et al (2014) Feasibility and validity of ecological momentary assessment in the investigation of suicide risk. Psychiatry Res 220:564–570. doi:10.1016/j.psychres.2014.08.019
Isacsson G, Rich CL, Jureidini J, Raven M (2010) The increased use of antidepressants has contributed to the worldwide reduction in suicide rates. Br J Psychiatry 196:429–433. doi:10.1192/bjp.bp.109.076166
Joiner TE, Brown JS, Wingate LR (2005) The psychology and neurobiology of suicidal behavior. Annu Rev Psychol 56:287–314. doi:10.1146/annurev.psych.56.091103.070320
Jollant F, Lawrence NS, Olie E et al (2010) Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. Neuroimage 51:1275–1281. doi:10.1016/j.neuroimage.2010.03.027
Jollant F, Lawrence NL, Olie E et al (2011) The suicidal mind and brain: a review of neuropsychological and neuroimaging studies. World J Biol Psychiatry 12:319–339. doi:10.3109/15622975.2011.556200
Lopez-Castroman J, Jaussent I, Beziat S et al (2012) Suicidal phenotypes associated with family history of suicidal behavior and early traumatic experiences. J Affect Disord 142:193–199. doi:10.1016/j.jad.2012.04.025
Lopez-Castroman J, Jaussent I, Beziat S et al (2014a) Increased severity of suicidal behavior in impulsive aggressive patients exposed to familial adversities. Psychol Med 44:3059–3068. doi:10.1017/S0033291714000646
Lopez-Castroman J, Olie E, Courtet P (2014b) Stress and vulnerability: a developing model for suicidal risk. In: Hudzik TJ, Cannon KE (eds) Suicide: phenomenology and neurobiology. Springer, Switzerland
MacLeod AK, Rose GS, Williams JMG (1993) Components of hopelessness about the future in parasuicide. Cogn Ther Res 17:441–455. doi:10.1007/BF01173056
McGowan PO, Sasaki A, D’Alessio AC et al (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12:342–348. doi:10.1038/nn.2270
Mee S, Bunney BG, Reist C et al (2006) Psychological pain: a review of evidence. J Psychiatr Res 40:680–690. doi:10.1016/j.jpsychires.2006.03.003
Meyer RE, Salzman C, Youngstrom EA et al (2010) Suicidality and risk of suicide – definition, drug safety concerns, and a necessary target for drug development: a consensus statement. J Clin Psychiatry 71:e1–e21. doi:10.4088/JCP.10cs06070blu
Nock MK, Borges G, Bromet EJ et al (2008) Cross-national prevalence and risk factors for suicidal ideation, plans and attempts. Br J Psychiatry 192:98–105. doi:10.1192/bjp.bp.107.040113
Olie E, Guillaume S, Jaussent I et al (2010) Higher psychological pain during a major depressive episode may be a factor of vulnerability to suicidal ideation and act. J Affect Disord 120:226–230. doi:10.1016/j.jad.2009.03.013
Olie E, Courtet P, Poulain V et al (2013) History of suicidal behaviour and analgesic use in community-dwelling elderly. Psychother Psychosom 82:341–343. doi:10.1159/000350504
Oquendo MA, Galfalvy H, Russo S et al (2004) Prospective study of clinical predictors of suicidal acts after a major depressive episode in patients with major depressive disorder or bipolar disorder. Am J Psychiatry 161:1433–1441. doi:10.1176/appi.ajp.161.8.1433
Oquendo MA, Miller JM, Sublette ME (2013) Neuroanatomical correlates of childhood sexual abuse: identifying biological substrates for environmental effects on clinical phenotypes. Am J Psychiatry 170:574. doi:10.1176/appi.ajp.2012.13030367
Posner K, Brown GK, Stanley B et al (2011) The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults. Am J Psychiatry 168:1266–1277. doi:10.1176/appi.ajp.2011.10111704
Raes F, Hermans D, Williams JMG et al (2005) Reduced specificity of autobiographical memory: a mediator between rumination and ineffective social problem-solving in major depression? J Affect Disord 87:331–335. doi:10.1016/j.jad.2005.05.004
Richard-Devantoy S, Berlim MT, Jollant F (2013) A meta-analysis of neuropsychological markers of vulnerability to suicidal behavior in mood disorders. Psychol Med 44:1663–1673. doi:10.1017/S0033291713002304
Rudd MD (2008) Suicide warning signs in clinical practice. Curr Psychiatry Rep 10:87–90. doi:10.1007/s11920-008-0015-4
Shneidman ES (1993) Suicide as psychache. J Nerv Ment Dis 181:145–147
Silverman MM, Berman AL, Sanddal ND et al (2007) Rebuilding the tower of Babel: a revised nomenclature for the study of suicide and suicidal behaviors. Part 1: background, rationale, and methodology. Suicide Life Threat Behav 37:248–263. doi:10.1521/suli.2007.37.3.248
Sullivan GM, Oquendo MA, Milak M et al (2015) Positron emission tomography quantification of serotonin(1A) receptor binding in suicide attempters with major depressive disorder. JAMA Psychiatry 72:169–178. doi:10.1001/jamapsychiatry.2014.2406
Vaiva G (2006) Effect of telephone contact on further suicide attempts in patients discharged from an emergency department: randomised controlled study. BMJ 332:1241–1245. doi:10.1136/bmj.332.7552.1241
Valente SM (1994) Messages of psychiatric patients who attempted or committed suicide. Clin Nurs Res 3:316–333. doi:10.1177/105477389400300404
Van Heeringen C, Bijttebier S, Godfrin K (2011) Suicidal brains: a review of functional and structural brain studies in association with suicidal behaviour. Neurosci Biobehav Rev 35:688–698. doi:10.1016/j.neubiorev.2010.08.007
Van Orden KA, Witte TK, Cukrowicz KC et al (2010) The interpersonal theory of suicide. Psychol Rev 117:575–600. doi:10.1037/a0018697
Williams KD (2007) Ostracism. Annu Rev Psychol 58:425–452. doi:10.1146/annurev.psych.58.110405.085641
Williams JM, Broadbent K (1986) Distraction by emotional stimuli: use of a Stroop task with suicide attempters. Br J Clin Psychol 25(Pt 2):101–110
Williams JMG, Pollock LR (2008) The pschology of suicidal behaviour. Wiley, West Sussex
Witte TK, Merrill KA, Stellrecht NE et al (2008) “Impulsive” youth suicide attempters are not necessarily all that impulsive. J Affect Disord 107:107–116. doi:10.1016/j.jad.2007.08.010
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Lopez-Castroman, J., Olié, E., Courtet, P. (2016). A Modern Semiology of Suicidal Behavior. In: Courtet, P. (eds) Understanding Suicide. Springer, Cham. https://doi.org/10.1007/978-3-319-26282-6_2
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DOI: https://doi.org/10.1007/978-3-319-26282-6_2
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