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Inherited and Acquired Thrombophilias and Adverse Pregnancy Outcomes

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Recurrent Pregnancy Loss

Abstract

Historically, much controversy has existed regarding the association of inherited thrombophilias with adverse pregnancy outcomes. Current guidelines recommend screening when there is a personal history of venous thromboembolism (VTE) or when there is a strong family history of thromboembolic disease, but our up to 40 % of physicians may screen contrary to current guidelines. This chapter summarizes the existing evidence for each inherited thrombophilia, and reviews current guidelines.

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Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Vanderbilt University, 80 Humphreys Center, Memphis, TN, 38120, USA

    William H. Kutteh MD, PhD, HCLD

Authors
  1. William H. Kutteh MD, PhD, HCLD
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Corresponding author

Correspondence to William H. Kutteh MD, PhD, HCLD .

Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er Sheva, Israel"., Be’er Sheva, Israel

    Asher Bashiri

  2. Recurrent Pregnancy Loss Clinic Fertility and IVF Unit Department of Obstetrics and Gynecology Soroka University Medical Center, Ben Gurion University of the Negev, Be’er Sheva, Israel, Be’er Sheva, Southern, Israel

    Avi Harlev

  3. Center for Reproductive Medicine, Cleveland Clinic, Cleveland, Ohio, USA

    Ashok Agarwal

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Kutteh, W.H. (2016). Inherited and Acquired Thrombophilias and Adverse Pregnancy Outcomes. In: Bashiri, A., Harlev, A., Agarwal, A. (eds) Recurrent Pregnancy Loss. Springer, Cham. https://doi.org/10.1007/978-3-319-27452-2_5

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  • DOI: https://doi.org/10.1007/978-3-319-27452-2_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-27450-8

  • Online ISBN: 978-3-319-27452-2

  • eBook Packages: MedicineMedicine (R0)

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