Abstract
Defining hypertension involves choosing a place in the relationship between increasing levels of blood pressure on the one hand, and the occurrence of outcomes like stroke, heart disease, and death on the other hand. The choice of this “cutpoint” between normotension and hypertension is made further challenging because one needs to take into account the benefits of antihypertensive therapies, as well as their risks. In this chapter we will define hypertension based on evidence that there exists for most target organs a point where the risks of treating blood pressure are outweighed by the benefits of reducing it. This cutpoint could well be different for the brain, the heart, and the kidney, the most commonly involved target organs of hypertension. However, in general the preponderance of evidence suggests that a systolic blood pressure value of 140 mmHg and a diastolic blood pressure value of 90 mmHg represent reasonable approximations of where the evidence indicates the current cutpoints should reside.
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Townsend, R.R., Steigerwalt, S.P. (2016). Blood Pressure: Definition, Diagnosis, and Management. In: Aiyagari, V., Gorelick, P. (eds) Hypertension and Stroke. Clinical Hypertension and Vascular Diseases. Humana Press, Cham. https://doi.org/10.1007/978-3-319-29152-9_1
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