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Toward Clinically Compatible Phase-Contrast Mammography

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Grating-Based X-Ray Phase-Contrast Mammography

Part of the book series: Springer Theses ((Springer Theses))

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Abstract

This chapter is dedicated to the clinical compatibility of laboratory-based phase-contrast mammography. First, we present which hardware changes and optimizations were conducted throughout the duration of this thesis, which enabled the first dose-compatible and rapid scan time phase-contrast mammograms of a freshly dissected mastectomy. In a next step, we quantitatively verify that the absorption mammograms obtained from the phase-contrast mammography unit meet the imaging criteria set by the American College of Radiology. Further, this chapter elaborates on the adaptation of tomosynthesis—which is nowadays common practice in clinical routine—towards phase-contrast and scatter-sensitive imaging. Note that some of the here presented results have been published as “Scherer, K. et al. Toward clinically compatible phase-contrast mammography. PLoS One 10, e0130776 (2015)”. Finally, this chapter concludes with a possible solution on how to present trimodal data in a comprehensive manner. The utilized fusion algorithm is provided by E. Coello (GE Global Research, Munich), was developed in collaboration with the TUM, and is based on the publications “Coello, E. Image fusion in X-Ray phase contrast imaging (Technische Universität München, Munich, 2014)”.

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Correspondence to Kai Hermann Scherer .

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Scherer, K.H. (2016). Toward Clinically Compatible Phase-Contrast Mammography. In: Grating-Based X-Ray Phase-Contrast Mammography. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-39537-1_7

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