Abstract
With the advancement of endoscopy and tissue biopsy, cytology has had an appreciably diminished role in the diagnosis of neoplasms of the gastrointestinal tubal tract (oral cavity to anus). However, because cytology of the GI tract still has a few advantages over histology, cytolopathologists will continue to encounter a number of these specimens in their practice. Some of these advantages include sampling a wider surface area, reaching less accessible areas (e.g., strictured tubal segments), yielding better preserved materials, and having decreased risks of procedural complications. In fact, cytology is the main diagnostic modality in certain clinical scenarios such as infectious and submucosal lesions. In this chapter, the focus will be on exfoliative cytology specimens dealing with mucosal-based lesions (Table 4.1). For those obtained from fine needle aspiration, essentially from submucosal lesions (Table 4.2), refer to the corresponding chapters on salivary gland, lymphoid, neural, neuroendocrine and mesenchymal neoplasms. In addition, anal cytology will be discussed along with uterine cervical cytology in the appropriate section.
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Diniz-Freitas M, García-García A, Crespo-Abelleira A, et al. Applications of exfoliative cytology in the diagnosis of oral cancer. Med Oral. 2004;9(4): 355–61.
Galloro G, Mignogna M, de Werra C, et al. The role of upper endoscopy in identifying oesophageal involvement in patients with oral pemphigus vulgaris. Dig Liver Dis. 2005;37(3):195–9.
Geisinger KR, Teot LA, Richter JE. A comparative cytopathologic and histologic study of atypia, dysplasia, and adenocarcinoma in Barrett’s esophagus. Cancer. 1992;69(1):8–16.
Isbister WH, Gupta RK. Colonoscopy, mucosal biopsy and brush cytology in the assessment of patients with colorectal inflammatory bowel disease. Surg Endosc. 1989;3(3):159–63.
Jhala N, Jhala D. Gastrointestinal tract cytology: advancing horizons. Adv Anat Pathol. 2003;10(5): 261–77.
Mokhtari M, Rasolmali R, Kumar PV. Pemphigus vulgaris of skin: cytological findings and pitfalls. Acta Cytol. 2012;56(3):310–4.
Mostaghni AA, Afarid M, Eghbali S, Kumar P. Evaluation of brushing cytology in the diagnosis of Helicobacter pylori gastritis. Acta Cytol. 2008;52(5): 597–601.
Navone R, Burlo P, Pich A, et al. The impact of liquid-based oral cytology on the diagnosis of oral squamous dysplasia and carcinoma. Cytopathology. 2007;18(6):356–60.
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Samedi, V.G., Bocklage, T. (2016). Gastrointestinal Tract. In: Pitfalls in Diagnostic Cytopathology With Key Differentiating Cytologic Features. Essentials in Cytopathology, vol 27. Springer, Cham. https://doi.org/10.1007/978-3-319-39809-9_4
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DOI: https://doi.org/10.1007/978-3-319-39809-9_4
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