Skip to main content

ST-Segment Elevation Myocardial Infarction (Lytic Candidate) on Oral Anticoagulant

  • Chapter
  • First Online:
Oral Anticoagulation Therapy

Abstract

Patients on oral anticoagulation who present with a ST-segment myocardial infarction and require fibrinolytics therapy represent a high patient population. With limited evidence to guide management, providers must assess risk versus benefit and attempt to mitigate bleeding events.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. O’Gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. J Am Coll Cardiol. 2013;61(4):e78–e140.

    Article  PubMed  Google Scholar 

  2. Lip GYH, Windecker S, Huber K, et al. Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions: a joint consensus document of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Intervention (EAPCI), and the European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS). Eur Heart J. 2014;35(45):3155–79.

    Article  CAS  PubMed  Google Scholar 

  3. Sarrinen S, Puolakka J, Boyd J, et al. Warfarin and fibrinolysis-a challenging combination: an observational cohort study. Scand J Trauma Resusc Emerg Med. 2011;19:21.

    Article  Google Scholar 

  4. Bovill E, Terrin M, Stump D, et al. Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction: results of the thrombolysis in myocardial infraction (TIMI) phase II trial. Ann Intern Med. 1991;115(4):256–65.

    Article  CAS  PubMed  Google Scholar 

  5. Stanley AG, Fletcher S, Tan A, Barnett DB. Is warfarin a contraindication to thrombolysis in acute ST elevation myocardial infarction? Heart. 2006;92(8):1145–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Brass L, Lichtman J, Wang Y, et al. Intracranial haemorrhage associated with thrombolytic therapy for elderly patients with acute myocardial infarction: results from the cooperative cardiovascular project. Stroke. 2000;31:1802–11.

    Article  CAS  PubMed  Google Scholar 

  7. Demaerschalk BM, Kleindorfer DO, Adeoye OM, et al. Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2016;47:581–641.

    Article  PubMed  Google Scholar 

  8. Larson DM, Duval S, Sharkey SW, et al. Safety and efficacy of a pharmaco-invasive reperfusion strategy in rural ST-elevation myocardial infarction patients with expected delays due to long-distance transfers. Eur Heart J. 2012;33(10):1232–40.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Craig J. Beavers PharmD, BCPS-AQ Card, CACP .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Beavers, C.J. (2017). ST-Segment Elevation Myocardial Infarction (Lytic Candidate) on Oral Anticoagulant. In: Kiser, K. (eds) Oral Anticoagulation Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-54643-8_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-54643-8_26

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-54641-4

  • Online ISBN: 978-3-319-54643-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics