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Nervous System

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Disorders of Blood Pressure Regulation

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

Abstract

The sympathetic nervous system plays an important role in the multifactorial pathogenesis of hypertensive disease. The objective of this chapter is to describe the role of adrenergic activation in the development of hypertension and to understand the neuroendocrine mechanisms contributing to the pathogenesis of hypertension.

The first part will describe methods used to investigate the adrenergic tone. In the second part, the physiological effects of sympathetic activation will be covered, as well as the pressor mechanisms of sympathetic activity that might result in hypertension. The third part will take into account the evidences indicating increased sympathetic activity in the different stages of the hypertensive disease. The last part will describe the mechanisms leading to sympathetic activation and new mechanisms hypothesized by data collected in recent years.

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Author information

Authors and Affiliations

  1. Cardiologia, Ospedale San Luca, IRCCS Istituto Auxologico Italiano, Milan, Italy

    Gino Seravalle

  2. Clinica Medica, Università Milano-Bicocca, Milan, Italy

    Gianmaria Brambilla, Daniela Prata Pizzala & Guido Grassi

Authors
  1. Gino Seravalle
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  2. Gianmaria Brambilla
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  3. Daniela Prata Pizzala
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  4. Guido Grassi
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Corresponding author

Correspondence to Guido Grassi .

Editor information

Editors and Affiliations

  1. Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon

    Adel E. Berbari

  2. Emeritus Professor of Medicine, University of Milano-Bicocca, Monza, Italy

    Giuseppe Mancia

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Seravalle, G., Brambilla, G., Pizzala, D.P., Grassi, G. (2018). Nervous System. In: Berbari, A., Mancia, G. (eds) Disorders of Blood Pressure Regulation. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-319-59918-2_6

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  • DOI: https://doi.org/10.1007/978-3-319-59918-2_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59917-5

  • Online ISBN: 978-3-319-59918-2

  • eBook Packages: MedicineMedicine (R0)

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