Abstract
Helath-related quality of life (HRQoL) in patients with reflux disease is significantly impaired in comparison to the general population. The level of impairment and types of problems experienced by GERD patients relate to symptom severity, the type and effectiveness of the treatment, sideeffects of surgery, and non-disease related factors such as the presence of other medical conditions, sex or anxiety. Several randomized trials comparing PPI therapy with laparoscopic antireflux surgery have been conducted, particularly over short-medium terms. Based on available studies, it can be concluded that in the short-medium terms laparoscopic antireflux surgery effectively alleviates symptoms of GERD, cures erosive esophagitis and improves quality of life. Postoperative adverse effects are usually mild and patient satisfaction good. For the long term (>10 years), limited data indicate decreasing effectiveness of laparoscopic antireflux surgery. Some patients may revert to the use of PPI therapy, or need revision surgery to improve symptom control following recurrent symptoms. HRQoL of patients with long term treatment success seems to be similar to that of the general population . Failed antireflux surgery and symptom recurrence significantly worsens the QoL in most patients. GERD is prevalent worldwide, and the disease burden seems to be increasing. The range of GERD prevalence estimates are 18.1–27.8% in North America, 8.8–25.9% in Europe, 2.5–7.8% in East Asia, 8.7–33.1% in the Middle East, 11.6% in Australia and 23.0% in South America [1, 2]. Prior use of non-steroidal anti-inflammatory drugs, smoking, excess body weight and gastrointestinal and cardiac conditions are associated with an increased risk of gastro-oesophageal reflux disease [3].
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Kellokumpu, I., Sihvo, E. (2018). Quality of Life Following Laparoscopic Antireflux Surgery for Primary and Recurrent Gastroesophageal Reflux Disease. In: Memon, M. (eds) Hiatal Hernia Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-64003-7_19
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