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Proteomic Research in Farm Animal Serum and Plasma

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Proteomics in Domestic Animals: from Farm to Systems Biology

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Abstract

Proteomics is one of the modern tools for in-depth study of the protein and peptide composition of complex protein mixtures and also has major applications in the field of animal science. Blood-derived fluids such as serum and plasma are rather unique biological samples as their protein content is contributed by the summation of all cellular proteome sets in the organism. Thus, they are a valuable source of information, reflecting the physiopathological status of the individuals. Being easy to obtain, they were and still are often the samples of choice to study physiology, investigate or diagnose diseases, as well as monitor and compare the influence of potentially harmful substances in different species.

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Abbreviations

2DE:

Two-dimensional electrophoresis

Apo A-I:

Apolipoprotein A-I

DIGE:

Fluorescence difference gel electrophoresis

GPA:

Growth-promoting agent

Hp:

Haptoglobin

MS:

Mass spectrometry

PTM:

Posttranslational modification

SAA:

Serum amyloid A

SELDI:

Surface-enhanced laser desorption/ionization

SRM:

Selected reaction monitoring

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Authors and Affiliations

  1. Toxalim (Research Center in Food Toxicology), Université de Toulouse, INRA, ENVT, INP-PURPAN, UPS, Toulouse Cedex 03, France

    Laura Soler

  2. Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

    Ingrid Miller

Authors
  1. Laura Soler
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  2. Ingrid Miller
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Corresponding author

Correspondence to Ingrid Miller .

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Editors and Affiliations

  1. Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, Lisbon, Portugal

    Andre Martinho de Almeida

  2. ERA Chair Laboratory, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia

    David Eckersall

  3. Institute of Medical Biochemistry, University of Veterinary Medicine, Vienna, Austria

    Ingrid Miller

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Soler, L., Miller, I. (2018). Proteomic Research in Farm Animal Serum and Plasma. In: de Almeida, A., Eckersall, D., Miller, I. (eds) Proteomics in Domestic Animals: from Farm to Systems Biology. Springer, Cham. https://doi.org/10.1007/978-3-319-69682-9_6

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