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Introduction: Coordinated Global Action Is Needed to Combat Antimicrobial Resistance

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Antimicrobial Resistance in the 21st Century

Part of the book series: Emerging Infectious Diseases of the 21st Century ((EIDC))

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Abstract

Antimicrobial resistance is a global dilemma that threatens the health and safety of populations in all countries of the world. Urgent actions are needed to be taken before it reaches a critical stage, when large numbers of people in communities cannot be treated for life-threatening infections due to lack of effective drugs. Although the threat is most imminent from antibacterial resistance to commonly used antibiotics for infections seen regularly in intensive care units and hospitals, it is more prevalent and widespread and involves a wide spectrum of microbes. This second edition of “Antimicrobial Resistance and Implications for the 21st Century” provides not only updates and advances since the original edition but provides a wider spectrum of topics in the issue. Although most chapters of this new edition address issues of common bacterial resistance, others provide up-to-date reviews on resistancetrends with viruses, including human immunodeficiency virus [HIV] and human herpes group of viruses.

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References

  1. Historical introduction. In: Greenwood D, Davey P, Wilcox M, editors. Antimicrobial chemotherapy. 5th ed. Oxford, UK: Oxford University Press; 2007. p. 1–10.

    Google Scholar 

  2. Davies J, Davies D. Origins of antibioptic resistance. Microbiol Mol Biol Rev. 2010;74:417–33.

    Article  CAS  Google Scholar 

  3. Levine DP. Vancomycin: a history. Clin Infect Dis. 2006;42(Suppl. 1):S5–12.

    Article  CAS  Google Scholar 

  4. Landman D, Gergescu C, Martin DA, Quale J. Polymyxins revisited. Clin Microbiol Rev. 2008;21:449–65.

    Article  CAS  Google Scholar 

  5. Gillings MR. Integrons: past, present and future. Microbiol Mol Biol Rev. 2014;778:257–77.

    Article  Google Scholar 

  6. Nathon C. Fresh approaches to anti-infective therapies. Sci Transl Med. 2012;4:140r2.

    Google Scholar 

  7. Hughes VM, Datta N. Conjugative plasmids in bacteria of the ‘pre-antibiotic’ era. Nature. 1983;302:725–6.

    Article  CAS  Google Scholar 

  8. D’Costa VM, King CE, Kalan L, et al. Antibiotic resistance is ancient. Nature. 2011;477:457–61.

    Article  Google Scholar 

  9. Deak D, Outterson K, Powers JH, Kesselhelm AS. Progress in the fight against multi-resistant bacteria? A review of US Food and Drug Administration—approved antibiotics, 2010–2015. Ann Intern Med. 2016;165:363–72.

    Article  Google Scholar 

  10. Van Boeckel TP, Brower C, Gilbert M, et al. Global trends in antimicrobial use in food animals. Proc Natl Acad Sci U S A. 2015;112:5649–54.

    Article  Google Scholar 

  11. Speksnijder DC, Mevius D, Bruscheke CJ, Wagenaar JA. Reduction of veterinary antimicrobial use in the Netherlands. The Dutch success model. Zoonoses Public Health. 2015;62(Suppl 1):79–87.

    Article  Google Scholar 

  12. Arcilla MS, van Hattem JM, Haverkate MR, et al. Import and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae by international travelers [COMBAT study]: a prospective, multicenter cohort study. Lancet Infect Dis. 2017;17:78–85.

    Article  Google Scholar 

  13. Laxminarayan R, Matsoso P, Pant S, Brower C, Rottingen JA, Klugman K, Davies S. Antimicrobials: access and sustainable effectiveness 1. Access to effective antimicrobials: a worldwide challenge. Lancet. 2016;387:168–75.

    Article  Google Scholar 

  14. Hamprecht A, Rohde AM, Behnke M, et al. Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk factors. J Chemother. 2016;71:2957–63.

    CAS  Google Scholar 

  15. Banerjee R, Teng CB, Cunningham SA, et al. Randomized trial of rapid multiplex polymerase chain reaction—based blood culture identification and susceptibility testing. Clin Infect Dis. 2015;61:1071–80.

    Article  CAS  Google Scholar 

  16. Wagner B, Filice GA, Drekonja D, et al. Antimicrobial stewardship programs in inpatient hospital settings: a systematic review. Infect Control Hosp Epidemiol. 2014;35:1209–28.

    Article  Google Scholar 

  17. Centers for Disease control and Prevention [CDC]. Office-related antibiotic prescribing for persons aged ≤ 14 years—United States, 1993–1994 to 2007–2008. MMWR Morb Mortal Wkly Rep. 2011;60:1153–6.

    Google Scholar 

  18. Lee GC, Reveles KR, Attridge RT, et al. Outpatient antibiotic prescribing in the United States: 2000 to 2010. BMC Med. 2014;12:96.

    Article  Google Scholar 

  19. Jones BE, Sauer B, jones MM, et al. Variation in outpatient antibiotic prescribing for acute respiratory infections in the veteran population. A cross-sectional study. Ann Intern Med. 2015;163:73–80.

    Article  Google Scholar 

  20. Fleming-Dutra KE, Hersh AL, Shapiro DJ, et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA. 2016;315:1864–73.

    Article  CAS  Google Scholar 

  21. Little P, Moore M, Kelly J, et al. the PIPS Investigators. Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic, factorial, randomized controlled trial. BMJ. 2014;348:g1606.

    Article  Google Scholar 

  22. Dar OA, Hasa R, Schlundt J, et al. Antimicrobials: access and sustainable effectiveness. Exploring the evidence base for national and regional policy interventions to combat resistance. Lancet. 2016;387:285–95.

    Article  Google Scholar 

  23. Spellberg B, Blaser M, Guidos RJ, et al. Infectious Disease Society of America [IDSA]. Combating antimicrobial resistance: policy recommendations to save lives. Clin Infect Dis. 2011;52(Suppl 5):S397-428.

    Google Scholar 

  24. Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria. 2016. Accessed at www.hhs.gov/sites/default/fioles/paccarb-final-report-03312016.pdf

  25. WHO. Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics. Accessed at http://www.int/medicines/publications/global-priority-list-antibiotic-resistant-bacteria/en/. On 31 Mar 2017.

  26. Slayton RB, Toth D, Lee BY, et al. Estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities—United States. MMWR Morb Mortal Wkly Rep. 2015;64:826.

    Article  Google Scholar 

  27. Cheng AC, Turnbridge J, Collignon P, Looke D, Barton M, Gottlieb T. Control of fluoroquinolone resistance through successful regulation, Australia. Emerg Infect Dis. 2012;18:1453–60.

    Article  CAS  Google Scholar 

  28. Zhu YG, Zhao Y, Li B, et al. Continental-scale pollution of estuaries with antibiotic resistant genes. Nat Microbiol. 2017;2:16270.

    Article  CAS  Google Scholar 

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Correspondence to I. W. Fong .

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Fong, I.W. (2018). Introduction: Coordinated Global Action Is Needed to Combat Antimicrobial Resistance. In: Fong, I., Shlaes, D., Drlica, K. (eds) Antimicrobial Resistance in the 21st Century. Emerging Infectious Diseases of the 21st Century. Springer, Cham. https://doi.org/10.1007/978-3-319-78538-7_1

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  • DOI: https://doi.org/10.1007/978-3-319-78538-7_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-78537-0

  • Online ISBN: 978-3-319-78538-7

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