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Amniotic Membrane Transplantation for the Treatment of Corneal Ulceration in Infectious Keratitis

  • Chapter
Cornea and External Eye Disease

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

Abstract

■ Corneal ulceration may occur in diverse types of infectious keratitis, e.g., in herpetic, bacterial, or parasitic infections

■ The diverse infectious entities can be distinguished by their clinical presentation

■ Before treatment, corneal scrapings or biopsies should be obtained for proper microbiological evaluation

■ The pathogenesis of infectious corneal ulcers includes micro-organism-related and immune-mediated factors

■ Amniotic membrane may have anti-inflammatory, antiangiogenic, and antimicrobial effects, and may promote re-epithelialization

■ An “onlay” (patch) or “inlay” (graft) technique can be used for amniotic membrane transplantation

■ Patients must be followed up closely after surgery to detect any spread of infection and failure of surgery

■ Appropriate antimicrobial medication should be given before and after surgery

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Authors and Affiliations

  1. Department of Ophthalmology, St. Franziskus Hospital, Hohenzollernring 74, 48145, Münster, Germany

    Arnd Heiligenhaus, Carsten Heinz & Dirk Bauer

  2. Department of Ophthalmology, University of Duisburg-Essen, 45122, Essen, Germany

    Klaus Schmitz, Christoph Tappeiner & Daniel Meller

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  1. Arnd Heiligenhaus
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  2. Carsten Heinz
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  4. Christoph Tappeiner
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  6. Daniel Meller
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Thomas Reinhard Frank Larkin

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Heiligenhaus, A., Heinz, C., Schmitz, K., Tappeiner, C., Bauer, D., Meller, D. (2008). Amniotic Membrane Transplantation for the Treatment of Corneal Ulceration in Infectious Keratitis. In: Reinhard, T., Larkin, F. (eds) Cornea and External Eye Disease. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33681-5_2

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