Abstract
Acral melanoma is a melanoma that affects acral areas of the skin, which is the most prevalent site of melanoma in non-Caucasians [5, 10]. Strictly speaking, acral lentiginous melanoma is not a synonym for acral melanoma. Acral lentiginous melanoma, originally described by Reed in 1976 [21], is one of the four histogenetic types defined by Clark et al. [6]. Almost all acral lentiginous melanomas occur on glabrous (nonhair- bearing) acral skin. Superficial spreading melanomas also occur on acral skin, but they are mostly seen on non-glabrous portions such as dorsal aspects of the hands and feet; however, superficial spreading melanomas can occur also on glabrous skin [12]. Furthermore, nodular melanomas are seen on both glabrous and nonglabrous acral skin.
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Literatur
Ackerman AB (1980) Malignant melanoma: a unifying concept. Hum Pathol 11:591–595
Balch CM, Buzaid AC, Soong S-J, et al. (2001) Final version of the American Joint Committee on cancer staging system for cutaneous melanoma. J Clin Oncol 19:3635–3648
Bastian BC (2003) Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer. Oncogene 22:3081–3086
Bastian BC, Kashani-Sabet M, Hamm H, et al. (2000) Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin. Cancer Res 60:1968–1973
Bellows C, Belafsky P, Fortgang IS, et al. (2001) Melanoma in African-Americans: trends in biological behavior and clinical characteristics over two decades. J Surg Oncol 78:10–16
Clark WH Jr, Goldman L, Mastrangelo MJ (1979) Human malignant melanoma. Grune and Stratton, New York
Curtin JA, Fridlyand J, Kageshita T, et al. (2005) Distinct set of genomic alterations in melanoma. N Engl J Med 353:2135–2147
Davies H, Bignell GR, Cox C, et al. (2002) Mutation of the BRAF gene in human cancer. Nature 417:949–954
Ferrara G, Argenziano G, Soyer P (2003) Melanocytic nevi of palms and soles. Am J Surg Pathol 27:411–412
Ishihara K, Saida T, Yamamoto A (2001) Updated statistical data for malignant melanoma in Japan. Int J Clin Oncol 6:109–116
Ishihara Y, Saida T, Miyazaki A, et al. (2006) Early acral melanoma in situ: correlation between the parallel ridge pattern on dermoscopy and microscopic features. Am J Dermatopathol 28:21–27
Kato T, Suetake T, Tabata N, et al. (1999) Epidemiology and prognosis of plantar melanoma in 62 Japanese patients over a 28-year period. Int J Dermatol 38:515–519
Kato T, Tabata N, Suetake T, et al. (1997) Non-pigmented nodular plantar melanoma in 12 Japanese patients. Br J Dermatol 136:207–211
Kawabata Y, Ohara K, Hino H, et al. (2001) Two kinds of Hutchinson's sign, benign and malignant. J Am Acad Dermatol 44:305–307
Kawabata Y, Tamaki K (1998) Distinctive dermatoscopic features of acral lentiginous melanoma in situ from plantar melanocytic nevi and their histopathologic correlation. J Cutan Med Surg 2:199–204
Koh HK, Michalik E, Sober AJ, et al. (1984) Lentigo maligna melanoma has no better prognosis than other types of melanoma. J Clin Oncol 2:994–1001
Kuchelmeister C, Schaumburg-Lever G, Garbe C (2000) Acral cutaneous melanoma in Caucasians: clinical features, histopathology and prognosis in 112 patients. Br J Dermatol 143:275–280
Maldonado JL, Fridlyand J, Patel H, et al. (2003) Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst 95:1878–1890
Miyazaki A, Saida T, Koga H, et al. (2005) Anatomical and histopathological correlates of the dermoscopic patterns seen in melanocytic nevi on the sole: a retrospective study. J Am Acad Dermatol 53:230–236
Oguchi S, Saida T, Koganehira Y, et al. (1998) Characteristic epiluminescent microscopic features of early malignant melanoma on glabrous skin: a videomicroscopic analysis. Arch Dermatol 134:563–568
Reed RJ (1976) Acral lentiginous melanoma. In: Hartmann W, Kay S, Reed RJ (eds) New concepts in surgical pathology of the skin. Wiley, New York, pp 89–90
Ronger S, Touzet S, Ligeron C, et al. (2002) Dermoscopic examination of nail pigmentation. Arch Dermatol 138:1327–1333
Saida T (1989) Malignant melanoma in situ on the sole of the foot: its clinical and histopathologic characteristics. Am J Dermatopathol 11:124–130
Saida T (1992) Heterogeneity of the site of origin of malignant melanoma in ungual areas: “subungual” malignant melanoma may be a misnomer. Br J Dermatol 126:529
Saida T (2000) Malignant melanoma on the sole: how to detect the early lesions efficiently. Pigment Cell Res 13 (Suppl 8):135–139
Saida T (2005) Lessons learned from studies of the development of early melanoma. Int J Clin Oncol 10:1371–1374
Saida T, Oshima Y (1989) Clinical and histopathologic characteristics of early lesions of subungual malignant melanoma. Cancer 63:556–560
Saida T, Miyazaki A, Grin CM (2005) Acro-lentiginous melanoma. In: Marghoob A, Braun R, Kopf A (eds) Atlas of dermoscopy. Taylor and Francis, London, pp 221–233
Saida T, Miyazaki A, Oguchi S, et al. (2004) Significance of dermoscopic patterns in detecting malignant melanoma on acral volar skin: results of a multi-center study in Japan. Arch Dermatol 140:1233–1238
Saida T, Oguchi S, Ishihara Y (1995) In vivo observation of magnified features of pigmented lesions on volar skin using videomicroscope: usefulness of epiluminescence technique in clinical diagnosis. Arch Dermatol 131:298–304
Saida T, Oguchi S, Miyazaki A (2002) Dermoscopy for acral pigmented skin lesions. Clin Dermatol 20:279–285
Seiji M, Takematsu H, Hosokawa M, et al. (1983) Acral melanoma in Japan. J Invest Dermatol 80 (Suppl):56s–60s
Signoretti S, Annessi G, Puddu P, et al. (1999) Melanocytic nevi of palms and soles: a histological study according to the planes of section. Am J Surg Pathol 23:283–287
Soon SL, Solomon AR, Papadopoulos D, et al. (2003) Acral lentiginous melanoma mimicking benign diseases: the Emory experience. J Am Acad Dermatol 48:183–188
Stevens NG, Liff JM, Weiss NS (1990) Plantar melanoma: Is the incidence of melanoma of the sole of foot really higher in blacks than whites? Int J Cancer 45:691–693
Weyers W, Euler M, Diaz-Cascajo C, et al. (1999) Classification of cutaneous malignant melanoma: a reassessment of histopathologic criteria for the distinction of different types. Cancer 86:288–299
Yamaura M, Takata M, Miyazaki A, et al. (2005) Specific dermoscopy patterns and amplifications of the cyclin D1 gene to define histopathologically unrecognizable early lesions of acral melanoma in situ. Arch Dermatol 141:1413–1418
Zalaudek I, Argenziano G, Soyer P, et al. (2004) Dermoscopy of subcorneal hematoma. Dermatol Surg 30:1229–1232
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(2007). Acral Melanoma. In: Soyer, H., Argenziano, G., Hofmann-Wellenhof, R., Johr, R. (eds) Color Atlas of Melanocytic Lesions of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35106-1_29
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DOI: https://doi.org/10.1007/978-3-540-35106-1_29
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