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Sentinel Node Detection in Pre-Operative Axillary Staging

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Breast Cancer

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Abstract

Sentinel lymph node (SLN) localisation and biopsy represent one of the most important developments in surgery and have already produced important changes in the management of patients affected by early infiltrating breast carcinoma. Sentinel lymph node biopsy (SLNB) was first applied in melanoma patients by Morton and colleagues (Morton et al. 1992); they intra-operatively injected the patent with vital blue dye close to the primary lesion, and the blue-stained SLN was later found by dissection, following tracer diffusion.

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Authors and Affiliations

  1. Division of Nuclear Medicine, European Institute of Oncology, Milan, Italy

    Giovanni Paganelli & Giuseppe Trifirò

  2. Division of Senology, European Institute of Oncology, Milan, Italy

    Oreste Gentilini & Mattia Intra

  3. Division of Pathology, European Institute of Oncology, Milan, Italy

    Giuseppe Viale

  4. Scientific Direction, European Institute of Oncology, Milan, Italy

    Umberto Veronesi

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  1. Giovanni Paganelli
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  2. Giuseppe Trifirò
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  3. Oreste Gentilini
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  4. Mattia Intra
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  5. Giuseppe Viale
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  6. Umberto Veronesi
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Editors and Affiliations

  1. Division of Nuclear Medicine Department of Diagnostic Imaging and Radiotherapy Fondazione IRCCS, Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milano, Italy

    Emilio Bombardieri MD

  2. Division of Medical Oncology Fondazione IRCCS, Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milano, Italy

    Luca Gianni MD

  3. Perspective Clinical Trials Fondazione IRCCS, Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milano, Italy

    Gianni Bonadonna MD (Chair) (Chair)

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Paganelli, G., Trifirò, G., Gentilini, O., Intra, M., Viale, G., Veronesi, U. (2008). Sentinel Node Detection in Pre-Operative Axillary Staging. In: Bombardieri, E., Gianni, L., Bonadonna, G. (eds) Breast Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36781-9_8

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