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Clinical Aspects of Acne Vulgaris

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Pathogenesis and Treatment of Acne and Rosacea

Abstract

Acne vulgaris, the most common disease of the skin, may present itself in a plethora of clinical forms, depending on the distribution, type of lesions, tendency to and manifestation of scarring, age at disease onset, and persistence of acne after the time of physiological regression [1]. The beginning of acne frequently occurs during the prepubertal period when adrenal androgens stimulate the pilosebaceous unit. Ovarian and testicular androgens play a key role in the development of acne in puberty. Consequently, acne vulgaris can begin in children as young as 6 or 7 years depending on the onset of adrenarche. Gradually, acne progresses in a cephalocaudal way resulting in the predominance of acne lesions on the chin, mandible, and neck just inferior to the mandible in adults and particularly adult women [2].

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Author information

Authors and Affiliations

  1. Department of Dermatology, Andreas Syngros Hospital, National and Capodistrian, University of Athens, Athens, Greece

    Andreas D. Katsambas

  2. Department of Dermatology, University of Leeds, Leeds, UK

    William J. Cunliffe

  3. Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany

    Christos C. Zouboulis

Authors
  1. Andreas D. Katsambas
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  2. William J. Cunliffe
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  3. Christos C. Zouboulis
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Corresponding author

Correspondence to Andreas D. Katsambas .

Editor information

Editors and Affiliations

  1. Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Dessau, Germany

    Christos C. Zouboulis

  2. Department of Dermatology, Andreas Syngros Hospital, University of Athens, Athens, Greece

    Andreas D. Katsambas

  3. Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Albert M. Kligman

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Katsambas, A.D., Cunliffe, W.J., Zouboulis, C.C. (2014). Clinical Aspects of Acne Vulgaris. In: Zouboulis, C., Katsambas, A., Kligman, A. (eds) Pathogenesis and Treatment of Acne and Rosacea. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69375-8_28

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  • DOI: https://doi.org/10.1007/978-3-540-69375-8_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69374-1

  • Online ISBN: 978-3-540-69375-8

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