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Bile Acids and Their Role in Cholesterol Homeostasis

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Cellular Lipid Metabolism

Abstract

Bile acids are synthesized from cholesterol and have long been thought to be just a degradation product with an additional function in food digestion. During the past decade many new functions of bile acids emerged and, instead of functioning at the interphase of the outside world and the body, bile acids turned out to be extremely important signal transduction molecules which play an important role in balancing flux through diverse metabolic pathways. In this chapter we focus on the function of bile acids in regulation of cholesterol homeostasis at both the cellular and organismal level.

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  1. Department of Medical Biochemistry (Room K1-106), Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

    Nora Bijl

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  1. Nora Bijl
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  2. Astrid van der Velde
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  3. Albert K. Groen
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    Bijl, N., van der Velde, A., Groen, A.K. (2009). Bile Acids and Their Role in Cholesterol Homeostasis. In: Ehnholm, C. (eds) Cellular Lipid Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00300-4_4

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