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Nebennierenrindenkarzinom

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Uroonkologie

Zusammenfassung

Die Inzidenz des seltenen Nebennierenrindenkarzinoms wird mit etwa 1–2/1 Mio./Jahr angegeben. Der häufig sehr aggressive Tumor führt zu etwa 0,2% aller Todesfälle aufgrund maligner Erkrankungen. Die Altersverteilung ist bimodal mit einem ersten Gipfel im Kindesalter und einem zweiten Gipfel in der 5.–6. Dekade. Frauen und Männer sind etwa im Verhältnis 1,5 ∶ 1 betroffen.

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Literatur

  • Abraham J, Bakke S, Rutt A et al. (2002) A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine and etoposide with daily mitotane as a P-glycoprotein antagonist. Cancer 94: 2333–2343

    Article  CAS  PubMed  Google Scholar 

  • Allolio B, Hahner S, Weismann D et al. (2004) Management of adrenocortical carcinoma. Clin Endocrinol (Oxf) 60: 273–287

    Article  Google Scholar 

  • Assie G, Antoni G, Tissier F et al. (2007) Prognostic parameters of metastatic adrenocortical carcinoma. J Clin Endocrinol Metab 92 (1): 148–54

    Article  CAS  PubMed  Google Scholar 

  • Baudin E, Pellegriti G, Bonnay M et al. (2001) Impact of monitoring plasma 1,1-dichlorodiphenildichloroethane (o,p′DDD) levels on the treatment of patients with adrenocortical carcinoma. Cancer 92: 1385–1392

    Article  CAS  PubMed  Google Scholar 

  • Becherer A, Vierhapper H, Potzi C et al. (2001) FDG-PET in adrenocortical carcinoma. Cancer Biother Radiopharm 16: 289–295

    Article  CAS  PubMed  Google Scholar 

  • Berruti A, Terzolo M, Pia A et al. (1998) Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma. Italian Group for the Study of Adrenal Cancer. Cancer 83: 2194–2200

    Article  CAS  PubMed  Google Scholar 

  • Caoili EM, Korobkin M, Francis IR et al. (2000) Delayed enhanced CT of lipid-poor adrenal adenomas. AJR Am J Roentgenol 175: 1411–1415

    CAS  PubMed  Google Scholar 

  • Fassnacht M, Hahner S, Banfelder N et al. (2005) Diagnostik und Therapie des Nebennierenrinden-Karzinoms. DÄ 102: 1670–1675

    Google Scholar 

  • Fassnacht M, Hahner S, Polat B et al. (2006) Efficacy of adjuvant radiotherapy of the tumor bed on local recurrence of adrenocortical carcinoma. J Clin Endocrinol Metab 91 (11): 4501–4

    Article  CAS  PubMed  Google Scholar 

  • Hahner S, Stuermer A, Kreissl M et al. (2008) [123 I]lodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes. J Clin Endocrinol Metab 93 (6): 2358–65

    Article  CAS  PubMed  Google Scholar 

  • Khan TS, Imam H, Juhlin C et al. (2000) Streptozocin and o,p′DDD in the treatment of adrenocortical cancer patients: long-term survival in its adjuvant use. Ann Oncol 11: 1281–1287

    Article  CAS  PubMed  Google Scholar 

  • Pena CS, Boland GW, Hahn PF et al. (2000) Characterization of indeterminate (lipid-poor) adrenal masses: use of washout characteristics at contrast-enhanced CT. Radiology 217: 798–802

    CAS  PubMed  Google Scholar 

  • Quinkler M, Hahner S, Wortmann S et al. (2008) Treatment of advanced adrenocortical carcinoma with erlotinib plus gemcitabine. J Clin Endocrinol Metab 93 (6): 2057–62

    Article  CAS  PubMed  Google Scholar 

  • Saeger W (2000) Histopathological classification of adrenal tumours. Eur J Clin Invest 30 Suppl 3: 58–62

    Article  PubMed  Google Scholar 

  • Schteingart DE, Doherty GM, Gauger PG et al. (2005) Management of patients with adrenal cancer: recommendations of an international consensus conference. Endocr Relat Cancer 12 (3): 667–80

    Article  CAS  PubMed  Google Scholar 

  • Terzolo M, Ali A, Osella G et al. (2000) The value of dehydroepiandrosterone sulfate measurement in the differentiation between benign and malignant adrenal masses. Eur J Endocrinol 142: 611–617

    Article  CAS  PubMed  Google Scholar 

  • Terzolo M, Angeli A, Fassnacht M et al. (2007) Adjuvant mitotane treatment for adrenocortical carcinoma. N Engl J Med 356 (23): 2372–80

    Article  CAS  PubMed  Google Scholar 

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Petersenn, S., Bockisch, A., Rübben, H., Mann, K. (2009). Nebennierenrindenkarzinom. In: Rübben, H. (eds) Uroonkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01382-9_19

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  • DOI: https://doi.org/10.1007/978-3-642-01382-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01381-2

  • Online ISBN: 978-3-642-01382-9

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