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PIP-Kinases as Key Regulators of Plant Function

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Lipid Signaling in Plants

Part of the book series: Plant Cell Monographs ((CELLMONO,volume 16))

Abstract

The phosphoinositide pathway arose early in evolution and is conserved in eukaryotic organisms of all kingdoms. Phosphoinositides derive from phosphatidylinositol (PtdIns) by sequential phosphorylation of the lipid head group and can interact with various protein partners to regulate their biochemical activity or subcellular localization. This chapter is concerned with PIP-kinases, the enzymes producing PtdIns-bisphosphates with regulatory function, such as the well-characterized PtdIns(4,5)P2 or the less-well understood PtdIns(3,4)P2 and PtdIns(3,5)P2. In recent years, the study of plant PIP-kinases has revealed new targets for perturbing plant phosphoinositide metabolism and enabled functional investigations on the roles of PtdIns-bisphosphates, including involvement in the regulation of cell polarity, guard cell function, defense responses, and stress signaling. Together with new techniques for lipid analysis and new tools for the visualization of specific lipids, these recent advances have opened the field to exciting discoveries, indicating central roles for PIP-kinases and phosphoinositide signaling in plant function and development.

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Acknowledgments

We thank Wendy Boss, Imara Perera, and Yang Ju Im (North Carolina State University) for helpful discussion. We also gratefully acknowledge the financial support through an Emmy Noether grant from the German Research Foundation (DFG, to I. H.).

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Authors and Affiliations

  1. Department of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, Georg-August-University Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany

    Ingo Heilmann

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  1. Till Ischebeck
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  2. Ingo Heilmann
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Correspondence to Ingo Heilmann .

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Editors and Affiliations

  1. Swammerdam Inst. Life Science, University of Amsterdam, Kruislaan 318, Amsterdam, 1098 SM, Netherlands

    Teun Munnik

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Ischebeck, T., Heilmann, I. (2010). PIP-Kinases as Key Regulators of Plant Function. In: Munnik, T. (eds) Lipid Signaling in Plants. Plant Cell Monographs, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03873-0_5

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